Exposure to Low-Dose Ionizing Radiation Linked to Solid Cancer Mortality
Medically reviewed by Drugs.com.
By Elana Gotkine HealthDay Reporter
MONDAY, Aug. 21, 2023 -- Protracted exposure to low-dose ionizing radiation is associated with an increased risk for solid cancer mortality, according to a study published online Aug. 16 in The BMJ.
David B. Richardson, Ph.D., from the University of California in Irvine, and colleagues examined the effect of protracted low-dose exposure to ionizing radiation on the risk for cancer in a multinational cohort study involving workers in the nuclear industry in France, the United Kingdom, and the United States. Participants included 309,932 workers with individual monitoring data for external exposure to ionizing radiation, with follow-up of 10.7 million person-years.
The researchers identified 103,553 deaths, including 28,089 due to solid cancers. There was a 52 percent increase in the estimated rate of mortality due to solid cancer with cumulative dose per Gy, which lagged by 10 years. The estimate of association was approximately doubled on restriction of the analysis to the low cumulative dose range (0 to 100 mGy) and with restricting the analysis to workers hired in more recent years, when estimates of occupational external radiation were more accurate. The estimated magnitude of the association was modestly affected by exclusion of deaths from lung cancer and pleural cancer, indirectly indicating that the association was not substantially confounded by smoking or asbestos exposure.
"The study provides evidence in support of a linear association between protracted low-dose external exposure to ionizing radiation and solid cancer mortality," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
![](/img/logo/vendor/healthday-logo.png)
© 2024 HealthDay. All rights reserved.
Posted August 2023
Read this next
Precision-Guided Treatment Improves Outcomes for High-Risk Pediatric Cancer
FRIDAY, June 28, 2024 -- Precision-guided treatment improves outcomes for children with high-risk cancer, according to a study published online June 6 in Nature Medicine. Loretta...
Surveillance IDs New Tumors in Children With Cancer Predisposition
FRIDAY, June 21, 2024 -- Standardized surveillance identifies new tumors among children with a wide spectrum of cancer predisposition syndromes (CPSs), according to a study...
FDA Approves Augtyro for NTRK-Positive Advanced Solid Tumors
THURSDAY, June 20, 2024 -- The U.S. Food and Drug Administration has approved Augtyro (repotrectinib), a next-generation tyrosine kinase inhibitor (TKI), for the treatment of...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.