Electrocochleography, MRI Most Reliable for Reclassifying Meniere Disease
By Elana Gotkine HealthDay Reporter
FRIDAY, Sept. 6, 2024 -- The most reliable approach to reclassifying patients with probable Meniere disease (MD) includes the combination of electrocochleography (ECochG) and magnetic resonance imaging (MRI) with MD-protocol, according to a study published in the November-December issue of the American Journal of Otolaryngology.
Roee Noy, M.D., from Rambam Health Care Campus in Haifa, Israel, and colleagues conducted a retrospective cohort study at a neurotology clinic to examine the efficacy of diagnostic tests in accurately reclassifying patients initially diagnosed with probable MD. Sixty-nine patients were included: 36.2, 30.4, and 33.4 percent were initially classified as definite MD, probable MD, and non-MD, respectively. Participants underwent a battery of tests, and sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios were calculated.
Patients were followed for a mean of 3.5 years. The researchers found that ECochG had the highest sensitivity (92 percent), with a negative likelihood ratio of 15 percent; the highest specificity was seen for MRI with MD-protocol, which also had a positive likelihood ratio of 100 percent. Lower sensitivity and specificity were seen for videonystagmography, the video head impulse test, and cervical vestibular-evoked myogenic potentials. Eighty-six percent of patients with probable MD were reclassified: 57 and 29 percent were diagnosed with definite MD and non-MD, respectively, consistent with their clinical course.
"The combination of ECochG and MRI with MD protocol provides valuable diagnostic support for patients with probable MD," the authors write. "Further studies should aim to confirm our findings and provide guidance for patients with uncertain diagnoses despite undergoing these two tests."
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted September 2024
Read this next
COVID-19 Mortality Higher for Leukemia, Myelodysplastic Syndrome Patients
THURSDAY, Nov. 21, 2024 -- The risk for COVID-19 hospitalization is low in adults with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), but these individuals have...
AI Model FastGlioma Can Detect Glioma Infiltration During Surgery
THURSDAY, Nov. 21, 2024 -- The artificial intelligence (AI) model FastGlioma can detect glioma infiltration during surgery, according to a study published online Nov. 13 in...
Nationwide, Couple-Based Reproductive Carrier Screening Program Demonstrates Feasbility
WEDNESDAY, Nov. 20, 2024 -- A nationwide, couple-based reproductive carrier screening program has demonstrated feasibility in informing reproductive decision-making, according to...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.