Skip to main content

Electrocochleography, MRI Most Reliable for Reclassifying Meniere Disease

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 6, 2024.

By Elana Gotkine HealthDay Reporter

FRIDAY, Sept. 6, 2024 -- The most reliable approach to reclassifying patients with probable Meniere disease (MD) includes the combination of electrocochleography (ECochG) and magnetic resonance imaging (MRI) with MD-protocol, according to a study published in the November-December issue of the American Journal of Otolaryngology.

Roee Noy, M.D., from Rambam Health Care Campus in Haifa, Israel, and colleagues conducted a retrospective cohort study at a neurotology clinic to examine the efficacy of diagnostic tests in accurately reclassifying patients initially diagnosed with probable MD. Sixty-nine patients were included: 36.2, 30.4, and 33.4 percent were initially classified as definite MD, probable MD, and non-MD, respectively. Participants underwent a battery of tests, and sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios were calculated.

Patients were followed for a mean of 3.5 years. The researchers found that ECochG had the highest sensitivity (92 percent), with a negative likelihood ratio of 15 percent; the highest specificity was seen for MRI with MD-protocol, which also had a positive likelihood ratio of 100 percent. Lower sensitivity and specificity were seen for videonystagmography, the video head impulse test, and cervical vestibular-evoked myogenic potentials. Eighty-six percent of patients with probable MD were reclassified: 57 and 29 percent were diagnosed with definite MD and non-MD, respectively, consistent with their clinical course.

"The combination of ECochG and MRI with MD protocol provides valuable diagnostic support for patients with probable MD," the authors write. "Further studies should aim to confirm our findings and provide guidance for patients with uncertain diagnoses despite undergoing these two tests."

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Posted September 2024

Read this next

Ultraprocessed Food Intake Contributes to All-Cause Mortality

MONDAY, April 28, 2025 -- Ultraprocessed food intake contributes to all-cause mortality, according to research published online April 28 in the American Journal of Preventive...

Burnout Still High for Veterans Health Administration Health Care Workers

MONDAY, April 28, 2025 -- Burnout remains above prepandemic levels for health care workers at the U.S. Veterans Health Administration (VHA), according to a study published online...

Exercise, Rehab Services Can Be Integrated Into Breast Cancer Care

MONDAY, April 28, 2025 -- Exercise and rehabilitation services for patients with breast cancer through a clinical workflow algorithm called CORE (Comprehensive Oncology...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.