Diabetes Risk in Overweight, Obese Teens Varies Substantially by Baseline HbA1c
By Lori Solomon HealthDay Reporter
TUESDAY, Jan. 30, 2024 -- Five-year diabetes risk among teens with overweight or obesity varies substantially by baseline HbA1c levels, according to a study published online Jan. 17 in JAMA Network Open.
Francis M. Hoe, M.D., from Kaiser Permanente Roseville Medical Center in California, and colleagues assessed the risk for future type 2 diabetes (T2D) among 74,552 adolescents (aged 10 to 17 years) with overweight and obesity.
The researchers found that the overall T2D incidence was 2.1 per 1,000 person-years, with a five-year cumulative incidence of 1.0 percent. A higher five-year cumulative T2D incidence was associated with higher baseline HbA1c (<5.5 percent to 5.5 to 5.6 percent: 0.3 to 0.5 percent; 5.7 to 5.8 percent: 1.1 percent; 5.9 to 6.0 percent: 3.8 percent; 6.1 to 6.2 percent: 11.0 percent; and 6.3 to 6.4 percent: 28.5 percent). Higher baseline HbA1c was associated with greater T2D risk compared with HbA1c <5.5 percent. Independent risk factors also included higher body mass index category, older age, female sex, and Asian or Pacific Islander race (hazard ratio, 1.7). Black race or Hispanic ethnicity were not risk factors compared with White race.
"These findings suggest that T2D surveillance in adolescents should be tailored based on HbA1c level, among other risk factors," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted January 2024
Read this next
Small Differences in Weight Change With First-Line Antidepressants
MONDAY, July 1, 2024 -- For eight first-line antidepressants, small differences are seen in mean weight change, with the least weight gain with bupropion, according to a study...
American Diabetes Association, June 21-24
The annual meeting of the American Diabetes Association was held this year from June 21 to 24 in Orlando, Florida, drawing more than 15,000 participants from around the world...
Few With Type 2 Diabetes Receive Guideline-Recommended CKD Screening
MONDAY, July 1, 2024 -- Fewer than one-quarter of patients with type 2 diabetes (T2D) receive recommended chronic kidney disease (CKD) screening, according to a study published...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.