AI Off-Label Tool Can Correctly Exclude Pathology in Chest Radiographs
By Elana Gotkine HealthDay Reporter
TUESDAY, Aug. 20, 2024 -- An artificial intelligence (AI) tool can exclude pathology, with an equal or lower rate of critical misses on radiographs than radiologists, according to a study published online Aug. 20 in Radiology.
Louis Lind Plesner, M.D., from Herlev and Gentofte Hospital in Denmark, and colleagues estimated the proportion of unremarkable chest radiographs in which AI can correctly exclude pathology without increasing diagnostic errors. Consecutive chest radiographs were obtained for 1,961 adults from Jan. 1 to 12, 2020, at four Danish hospitals. Chest radiographs were labeled as remarkable or unremarkable based on predefined findings; radiology reports were similarly classified. A commercial AI tool was adapted to output the probability of chest radiograph remarkableness, which was used to calculate specificity at different AI sensitivities.
The researchers found that based on the reference standard, 62.8 and 37.2 percent of chest radiographs were labeled as remarkable and unremarkable, respectively. The AI had specificity of 24.5, 47.1, and 52.7 percent at sensitivity of 99.9, 99.0, and 98.0 percent, respectively. With AI sensitivity fixed to be similar to that of radiology reports (87.2 percent), the missed findings of AI and reports had 2.2 and 1.1 percent classified as critical, and 4.1 and 3.6 percent and 6.5 and 8.1 percent classified as clinically significant and clinically insignificant, respectively. The AI tool exhibited ≤1.1 percent critical misses at sensitivities ≥95.4 percent.
"These results should be evaluated in a prospective study due to the high potential for mitigating workload challenges in radiology departments," the authors write.
Several authors disclosed ties to the pharmaceutical and medical device industries.
Editorial (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted August 2024
Read this next
Inflammation in Childhood Linked to Onset of Mental Health Disorders
FRIDAY, Aug. 23, 2024 -- Low-grade systemic inflammation across childhood and adolescence is associated with the subsequent onset of mental health disorders, according to a study...
Two-Thirds of COPD Hospitalized Patients Misuse Inhalers
FRIDAY, Aug. 23, 2024 -- Among patients hospitalized with a diagnosis of chronic obstructive pulmonary disorder (COPD), two-thirds of inhalers assessed at admission are misused...
CMR-Modeled PCWP Independent Risk Factor for Heart Failure
THURSDAY, Aug. 22, 2024 -- Elevated cardiovascular magnetic resonance (CMR) imaging-modeled pulmonary capillary wedge pressure (PCWP) is an independent risk factor for heart...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.