ADHD Meds May Help Control Opioid Use Disorder in Pregnancy
By Lori Solomon HealthDay Reporter
TUESDAY, June 25, 2024 -- Psychostimulants may help opioid use disorder (OUD) outcomes in pregnant women, according to a study published online June 11 in Nature Mental Health.
Kevin Y. Xu, M.D., M.P.H., from the Washington University School of Medicine in St. Louis, and colleagues used U.S. multistate administrative data to examine the risks and benefits of attention-deficit/hyperactivity disorder (ADHD) medication among 3,247 pregnant women initiating OUD treatment, with 5 percent receiving psychostimulants.
The researchers found that compared to peers not receiving psychostimulants, individuals receiving psychostimulants had greater buprenorphine (adjusted relative risk, 1.81) but lower methadone initiation (adjusted relative risk, 0.39). Among psychostimulant recipients who initiated buprenorphine, lower buprenorphine discontinuation was seen among those receiving psychostimulants versus nonrecipients (adjusted hazard ratio, 0.77). Person-days (defined by psychostimulant fills) were associated with fewer substance use disorder-related admissions versus days without fills in within-person case-crossover analyses (odds ratio, 0.50).
"These findings highlight important potential benefits of pharmacologically treating ADHD with stimulants in pregnant people with concomitant OUD and ADHD," the authors write. "Future studies are warranted to clarify pregnancy and neonatal outcomes when treating this specific population to further inform share decision-making."
One author disclosed ties to the pharmaceutical industry.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted June 2024
Read this next
Only One-Quarter of Adults Who Needed Opioid Use Disorder Meds in 2022 Received Them
THURSDAY, June 27, 2024 -- Only one-quarter of adults who needed opioid use disorder (OUD) treatment in 2022 received medications for OUD, according to research published in the...
Pediatric Surgical Opioid Prescribing Concentrated Among a Few Procedures
WEDNESDAY, June 26, 2024 -- Pediatric surgical opioid prescribing is concentrated among a small number of procedures, especially tonsillectomy and/or adenectomy, according to a...
About One-Third of Mental Health Facilities Offer Meds for Opioid Addiction
THURSDAY, June 20, 2024 -- About one-third of community outpatient mental health treatment facilities (MHTFs) offer medications for opioid use disorder (MOUD), according to a...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.