Generic name: urea topical [ YOO-ree-a-TOP-ik-al ]
Brand names: Aqua Care, Aquaphilic with Urea, Atrac-Tain, Carb-O-Philic/20, Carmol, ... show all 36 brands Carmol 10, Carmol-20, CEM-Urea, Epimide 50, Gormel, Gormel 10, Hydro 40, Kera Nail, Kera-42, Nutraplus, Rea-Lo, Rinnovi Nail System, U-Kera, Umecta Mousse, Uramaxin, Urea Nail Gel, Ureacin-10, Ureacin-20, Ure-K, Xurea, Aluvea, Carb-O-Philic/10, Cerovel, Dermasorb XM, Hydro 35, Keralac, Kerol, Remeven, Umecta, Utopic, X-Viate
Drug class: Topical emollients

Medically reviewed by Drugs.com on Sep 20, 2023. Written by Cerner Multum.

What is Xurea?

There are many brands and forms of urea topical available and not all brands are listed on this leaflet.

Xurea (for the skin) is used to soften rough or dry skin caused by skin conditions such as eczema, psoriasis, keratosis, and others. This medicine is also used to soften damaged fingernails or toenails so they can be removed without surgery.

Xurea may also be used for purposes not listed in this medication guide.

Xurea side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Xurea may cause serious side effects. Stop using Xurea and call your doctor at once if you have:

• severe redness or irritation of treated skin.

Common side effects of Xurea may include:

• mild itching; or

• mild burning or stinging.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Xurea if you are allergic to it.

FDA pregnancy category C. It is not known whether Xurea will harm an unborn baby. Do not use Xurea without a doctor's advice if you are pregnant.

It is not known whether urea topical passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

How should I use Xurea?

Xurea is available in many different forms (cream, lotion, ointment, liquid, gel, foam, shampoo, and others) for use on the skin or the scalp. Use your medicine exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Xurea is for use only on the skin. If this medication gets in your eyes, nose, mouth, rectum, or vagina, rinse with water.

Use a mild soap or cleanser to wash the skin or nail area to be treated. Xurea may work best if the skin or nail to be treated is left slightly damp before the medicine is applied.

Apply a thin layer of this medicine to the affected skin and rub it in as completely as possible.

When applying Xurea to the nails, avoid getting any medicine on the cuticles or surrounding skin. Apply generously to the nail and allow the medicine to dry. You may cover the nail with a bandage or gauze if your doctor advises. The treated nail should be easily removed after several days.

Shake the Xurea foam well just before each use. Other forms of this medicine may also need to be shaken before use. Follow all directions on th medicine label.

Wash your hands with soap and water after applying this medicine, unless you are treating the skin on your hands.

Call your doctor if your symptoms do not improve, or if they get worse while using Xurea.

Store at room temperature away from moisture and heat. Do not freeze. Keep the medicine container tightly closed when not in use.

Keep the foam canister away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty foam canister.

Related/similar drugs

ammonium lactate topical, Temovate, urea topical, AmLactin, dimethicone topical, lactic acid topical, Clobevate, Clobex

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Xurea?

Do not use Xurea on open wounds, burns, or areas of swollen skin. If this medication gets in your eyes, nose, mouth, rectum, or vagina, rinse with water.

What other drugs will affect Xurea?

It is not likely that other drugs you take orally or inject will have an effect on topically applied urea. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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