Multihance

Generic name: gadobenate dimeglumine [ GAD-oh-BEN-ate-dye-MEG-loo-meen ]
Drug class: Magnetic resonance imaging contrast media

Medically reviewed by Drugs.com on Apr 15, 2024. Written by Cerner Multum.

What is Multihance?

Multihance is a contrast agent that has magnetic properties. It is used in combination with magnetic resonance imaging (MRI) or magnetic resonance angiography (MRA) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on MRI or MRA.

Multihance is used to help diagnose certain disorders of the brain and spine (central nervous system).

Multihance is also used in adults to diagnose atherosclerosis (clogged arteries).

Multihance may also be used for purposes not listed in this medication guide.

Multihance side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Some side effects of gadobenate dimeglumine may occur up to several days after injection.

Multihance can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:

• burning, itching, swelling, scaling, and tightening or hardening of your skin;

• skin redness or discoloration;

• muscle weakness;

• joint stiffness in your arms, hands, legs, or feet;

• pain; or

• tiredness, trouble moving.

Multihance may cause serious side effects. Call your doctor at once if you have:

• kidney problems--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;

• a seizure (convulsions);

• pounding heartbeats or fluttering in your chest; or

• pain, burning, swelling, blistering, or skin changes where the injection was given.

Common side effects of Multihance may include:

• headache;

• feeling hot;

• nausea; or

• burning around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Multihance can cause a life-threatening condition in people with advanced kidney disease. Before receiving this medicine, tell your doctor if you have kidney disease or if you are on dialysis. You may not be able to receive this medicine. Also tell your doctor if you have recently received any contrast agents similar to this medicine.

Before taking this medicine

Multihance can cause a life-threatening condition in people with advanced kidney disease. Ask your doctor about your individual risk.

Multihance can stay in your body for months or years after you receive Multihance. It is not known whether this could cause any health problems in people whose kidneys work properly. Tell your doctor if you have had repeated scans with a contrast agent, and provide the date of your last scan.

You should not receive Multihance if you are allergic to it.

Tell your doctor if you have ever had:

• Dubin Johnson syndrome;

• any type of reaction to a contrast agent;

• diabetes;

• asthma, hay fever, food or drug allergies;

• heart rhythm disorder, high blood pressure; or

• liver or kidney disease.

Tell your doctor if you are pregnant or breastfeeding.

How is Multihance given?

Multihance is given as an infusion into a vein. A healthcare provider will give you this injection.

You will be watched for a short time to make sure you do not have an allergic reaction.

What happens if I miss a dose?

In a medical setting you are not likely to miss a dose.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid after receiving Multihance?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Multihance?

Tell your doctor about all your other medicines, especially:

• cisplatin;

• daunorubicin, doxorubicin;

• etoposide;

• methotrexate;

• paclitaxel;

• tamoxifen; or

• vinblastine, vincristine.

This list is not complete. Other drugs may affect Multihance, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2025 Cerner Multum, Inc. Version: 5.03.