Mirvetuximab soravtansine

Generic name: mirvetuximab soravtansine [ MIR-ve-TUX-i-mab-SOE-rav-TAN-seen ]
Brand name: Elahere
Dosage form: intravenous solution (gynx 100 mg/20 mL)
Drug class: Miscellaneous antineoplastics

Medically reviewed by Drugs.com on Feb 21, 2025. Written by Cerner Multum.

What is mirvetuximab soravtansine?

Mirvetuximab soravtansine is used to treat adults with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who are no longer responding to platinum-based chemotherapy and have received 1 to 3 types of chemotherapy.

Your doctor will perform a tests to make sure mirvetuximab soravtansine is the right treatment for you.

Mirvetuximab soravtansine may also be used for purposes not listed in this medication guide.

Mirvetuximab soravtansine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mirvetuximab soravtansine may cause serious side effects. Call your doctor at once if you have:

• dry eyes, sensitivity to light, blurred vision, eye pain, or new or worsening vision changes;

• cough, chest pain, trouble breathing, shortness of breath; or

• numbness, tingling, or burning pain in your hands or feet.

Common side effects of mirvetuximab soravtansine may include:

• abnormal lab results;

• nausea, stomach pain, diarrhea, constipation;

• fever, mouth sores, skin sores, sore throat, cough; or

• pale skin, tiredness, feeling light-headed or short of breath, cold hands and feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Call your doctor at once if you have any eye problems, including blurred vision, eye pain, or new or worsening vision problems.

Before taking this medicine

Tell your doctor if you have or have ever had:

• vision or eye problems; or

• liver problems.

May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using mirvetuximab soravtansine and for at least 7 months after your last dose. Tell your doctor if you become pregnant.

You may need to have a negative pregnancy test before starting this treatment.

Do not breastfeed while using mirvetuximab soravtansine, and for at least 1 month after your last dose.

How is mirvetuximab soravtansine given?

Follow all directions on your prescription label and read all medication guides or instruction sheets.

Your doctor may change, delay, or permanently discontinue your treatment with mirvetuximab soravtansine if you have certain side effects.

Mirvetuximab soravtansine is usually given every 3 weeks as an infusion into your vein. Your doctor will decide how many cycles you need.

You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your doctor has prescribed.

You may need frequent vision exams.

Your doctor may prescribe eye drops before and during your treatment with mirvetuximab soravtansine. You should use these eye drops as directed by your doctor.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your mirvetuximab soravtansine injection.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid while receiving mirvetuximab soravtansine?

Avoid wearing contact lenses while using mirvetuximab soravtansine unless your doctor tells you to.

What other drugs will affect mirvetuximab soravtansine?

Tell your doctor about all your current medicines. Many drugs can affect mirvetuximab soravtansine, especially:

• nefazodone;

• cancer medicine--ceritinib, idelalisib, ribociclib, tucatinib;

• an antibiotic--clarithromycin, telithromycin;

• antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole; or

• antiviral medicine for HIV or hepatitis C--boceprevir, cobicistat, dasabuvir, elvitegravir, indinavir, lopinavir/ritonavir, nelfinavir, ombitasvir, paritaprevir saquinavir, telaprevir, tipranavir.

This list is not complete and many other drugs may affect mirvetuximab soravtansine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Mirvetuximab soravtansine Biosimilars

Biosimilar and interchangeable products are biological products that are highly similar to and have no clinically meaningful differences from the reference product.

Reference products

These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There is 1 for mirvetuximab soravtansine.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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