Mavorixafor

Generic name: mavorixafor [ MAV-or-IX-a-for ]
Brand name: Xolremdi
Dosage form: oral capsule (100 mg)
Drug class: Other immunostimulants

Medically reviewed by Drugs.com on Jul 2, 2024. Written by Cerner Multum.

What is mavorixafor?

Mavorixafor is used in adults and children at least 12 years old with WHIM syndrome to help fight infections.

Mavorixafor may also be used for purposes not listed in this medication guide.

Mavorixafor side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have fast or pounding heartbeats, shortness of breath, and sudden dizziness.

Common side effects of mavorixafor may include:

• dizziness;

• nosebleed;

• vomiting;

• skin rash;

• easy bruising, unusual bleeding, purple or red spots under your skin; or

• runny or stuffy nose, sneezing, and itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Tell your doctor about all your other medicines. Some drugs should not be used with mavorixafor.

Mavorixafor can cause a serious heart problem.

Before taking this medicine

Tell your doctor about all your other medicines. Some drugs should not be used with mavorixafor.

Tell your doctor if you have or have ever had:

• heart problems, including long QT syndrome (in you or a family member); or

• liver or kidney disease.

May harm an unborn baby. Use effective birth control while using mavorixafor and for at least 3 weeks after your last dose. Tell your doctor if you become pregnant.

You may need to have a negative pregnancy test before starting this treatment.

Do not breastfeed while using mavorixafor, and for at least 3 weeks after your last dose.

Related/similar drugs

Xolremdi

How should I take mavorixafor?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Doses are based on weight. Your dose may change if you gain or lose weight.

Take on an empty stomach in the morning, 30 minutes before a meal.

Swallow the capsule whole and do not crush, chew, break, or open it.

You may need medical tests to check your heart function.

Store this medicine in the refrigerator, tightly closed in the original container away from moisture. Do not freeze.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking mavorixafor?

Grapefruit may interact with mavorixafor and cause side effects. Avoid consuming grapefruit products.

What other drugs will affect mavorixafor?

Mavorixafor can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Tell your doctor about all your current medicines. Many drugs can affect mavorixafor, especially:

• nefazodone;

• St. John's wort;

• an antibiotic--clarithromycin, rifabutin, rifampin, rifapentine, telithromycin;

• antifungal medicine--itraconazole, ketoconazole;

• antiviral medicine for HIV or hepatitis C--boceprevir, cobicistat, dasabuvir, elvitegravir, indinavir, lopinavir/ritonavir, nelfinavir, ombitasvir, paritaprevir saquinavir, telaprevir, tipranavir;

• cancer medicine--apalutamide, enzalutamide, mitotane;

• seizure medicine--carbamazepine, oxcarbazepine, phenytoin, primidone; or

• steroid medicine--dexamethasone, prednisone.

This list is not complete and many other drugs may affect mavorixafor. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2024 Cerner Multum, Inc. Version: 1.01.