Generic name: acoramidis
Brand name: Attruby
Dosage form: oral tablet (356 mg)
Drug class: Transthyretin stabilizers

Medically reviewed by Drugs.com on Jan 14, 2025. Written by Cerner Multum.

What is acoramidis?

Acoramidis is used in adults to treat cardiomyopathy.

Acoramidis may also be used for purposes not listed in this medication guide.

Acoramidis side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Common side effects of acoramidis may include:

• stomach pain; or

• diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not take acoramidis if you are allergic to it.

It is not known if acoramidis will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using acoramidis.

How should I take acoramidis?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Acoramidis is usually taken twice per day (about 12 hours apart) with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Store this medicine in the original container at room temperature away from moisture and heat.

Acoramidis dosing information

Usual Adult Dose for Hypertrophic Cardiomyopathy:

Recommended dosage: 712 mg orally twice daily

Comments:
-Can be administered with or without food

Use: For the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

Usual Adult Dose for Amyloidogenic Transthyretin Amyloidosis:

Recommended dosage: 712 mg orally twice daily

Comments:
-Can be administered with or without food

Use: For the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking acoramidis?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect acoramidis?

Other drugs may affect acoramidis, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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