Skip to main content

How is Zilretta administered?

Medically reviewed by Judith Stewart, BPharm. Last updated on May 10, 2024.

Official answer

by Drugs.com

Zilretta (triamcinolone acetonide extended-release injectable suspension) is administered as an intra-articular injection into the knee joint.

Zilretta is indicated for the management of osteoarthritis pain of the knee.

Zilretta contains triamcinolone acetonide, a commonly administered, short-acting corticosteroid formulated in poly lactic-co-glycolic acid (PLGA) microspheres to provide long acting pain relief over 12 weeks.

Zilretta works by reducing inflammation to decrease acute episodes of pain and increase joint mobility.

Common side effects of Zilretta include joint pain, headache, joint swelling, back pain, sore throat and runny nose, upper respiratory tract infection, and bruising.

Read next

Where should you not use triamcinolone acetonide cream?

You should not use topical corticosteroids like triamcinolone acetonide cream on your face, groin, or axillae (underarm, armpit) unless directed by your doctor. Using triamcinolone in these areas may lead to unwanted side effects like acne, prominent blood vessels, skin thinning (atrophy), changes in skin color or unwanted hair growth. Continue reading

Is triamcinolone acetonide an antifungal cream?

Triamcinolone is not an antifungal cream. It is a topical corticosteroid (“steroid”) cream used to decrease inflammation and itching of skin conditions such as plaque psoriasis, atopic dermatitis (eczema) and allergic reactions. Topical corticosteroids work by reducing inflammation (redness, swelling, itching) on the skin. Continue reading

Is triamcinolone good for poison ivy?

Steroid prescription creams or ointments like high-potency triamcinolone 0.5% may be helpful during the first few days of a poison ivy rash on a small area, but have little effect once the fluid-filled blisters have appeared. Over-the-counter (OTC) products like hydrocortisone cream 1% are not usually strong enough for poison ivy. Your doctor may prescribe oral prednisone pills for a more severe rash. Continue reading

Related medical questions

Drug information

Related support groups