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Can you take Lunesta (eszopiclone) every night?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on Nov 12, 2024.

Official answer

by Drugs.com

The FDA-approved label for Lunesta (eszopiclone) does not specify how long the medication can be used to treat insomnia. Follow your healthcare provider’s instructions on how to take this medication. It is typically taken every night until you and your healthcare provider decide you can try to stop taking it to see if your sleeping problems have gotten better. If your insomnia gets worse or does not get better within 7-10 days of taking Lunesta, contact your prescriber.

Lunesta has been studied for up to 12 months in people with chronic insomnia, where it has been proven to work well during this time. The only side effect reported by more than 5% of people taking Lunesta during the 12-month study was an unpleasant taste. It is not known how well it works beyond this time, nor if it is safe.

How do you take Lunesta?

Lunesta comes in three different tablet strengths: 1 mg, 2 mg, and 3 mg. It is recommended to start with the lowest dose (1 mg) to lower your risk of next-day impairment. The usual dose is to take 1 mg by mouth right before bedtime, making sure you have at least 7-8 hours left before you need to wake up. Do not take Lunesta if you plan to be awake for a while, because this can lead to memory problems, hallucinations, and dizziness.

If the 1 mg strength does not seem to be working for you, your prescriber may raise your dose to a maximum of 3 mg per night. Those who are older in age, have severe liver problems, or are taking certain medications that interact with Lunesta should not take more than 2 mg per night.

Lunesta should not be taken with or right after a heavy, high-fat meal, because this can delay the time it takes for it to start working.

This is not all the information you need to know about Lunesta (eszopiclone) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.

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References

Heesch, C. B. 2014. The long-term use of sedative hypnotics in chronic insomnia. In: Mental Health Clinician. DOI: https://doi.org/10.9740/mhc.n190097

Lunesta [package insert]. 2023. Sumitomo Pharma America, Inc. Accessed 11/08/24 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fd047b2b-05a6-4d99-95cb-955f14bf329f

Roth, T., et. al. 2005. An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia. In: Sleep Medicine. DOI: https://doi.org/10.1016/j.sleep.2005.06.004

Sateia, M. J., et. al. 2017. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline. In: Journal of Clinical Sleep Medicine. DOI: https://doi.org/10.5664/jcsm.6470

U.S. Food and Drug Administration. (2018). Questions and answers: Risk of next-morning impairment after use of insomnia drugs; FDA requires lower recommended doses for certain drugs containing zolpidem (Ambien, Ambien CR, Edluar, and Zolpimist). Accessed 11/12/2024 at https://www.fda.gov/drugs/drug-safety-and-availability/questions-and-answers-risk-next-morning-impairment-after-use-insomnia-drugs-fda-requires-lower

Zee, P. C., et. al. 2023. Long-Term Use of Insomnia Medications: An Appraisal of the Current Clinical and Scientific Evidence. In: Journal of Clinical Medicine. DOI: https://doi.org/10.3390/jcm12041629

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