Can you drink alcohol while taking Prolia?
While there are no known drug interactions between Prolia (generic name: denosumab) and alcohol, you should check with your doctor first before you combined the two. Some research has shown that drinking alcohol may increase your risk of osteoporosis, a bone fracture or impaired healing after a fracture.
Alcohol can affect the amount of calcium that is available in your body to make bones more strong. Drinking alcohol may also increase your risk for dizziness, sleepiness or a fall that can lead to an injury or bone fracture.
Excessive alcohol consumption may cause liver problems like cirrhosis, hepatitis or liver inflammation. However, no clinical studies have been done to evaluate how liver disease affects Prolia.
If you choose to drink, contact your healthcare provider first. Ask if it is safe to drink alcohol with Prolia, how much you can safely consume, or if you should stop drinking altogether.
How does Prolia work in osteoporosis?
Prolia (denosumab) is classified as a RANK ligand (RANKL) inhibitor and works to increase bone density. It does this by stopping cells that lead to bone breakdown and damage in your body.
You will receive your Prolia injection from your healthcare provider at their office or clinic. It is a prescription medicine injected under the skin (a subcutaneous injection) and is given once every 6 months. It is used along with daily oral vitamin D and calcium supplements as directed by your doctor.
The FDA has approved Prolia for:
- the treatment of postmenopausal women with osteoporosis at high risk for fracture
- the treatment of bone loss in patients with prostate cancer or breast cancer undergoing hormone ablation therapy
- the treatment of men with osteoporosis at high risk for fracture to increase bone mass
- the treatment of osteoporosis due to use of corticosteroid medicines (such as prednisone) in men and women at high risk of fracture.
This is not all the information you need to know about Prolia (denosumab) for safe and effective use and does not take the place of your doctor’s directions. Review the full Prolia product information and discuss this information and any questions you have with your doctor or other health care provider.
Related questions
References
- Prolia (denosumab) prescribing information. Revised 5/2021. Amgen Inc. Accessed Apr 19, 2022 at https://www.pi.amgen.com/-/media/Project/Amgen/Repository/pi-amgen-com/Prolia/prolia_pi.pdf
- Sampson HW. Alcohol and Other Factors Affecting Osteoporosis Risk in Women. National Institute of Alcohol Abuse and Alcoholism. Accessed Apr 19, 2022 at https://pubs.niaaa.nih.gov/publications/arh26-4/292-298.htm
Read next
Does Prolia cause weight gain?
Prolia (denosumab) has not been associated with weight gain in clinical studies. Prolia can cause peripheral edema (fluid retention) or swelling, and this may lead to weight gain in some people. Continue reading
Does Prolia increase bone density?
Prolia (denosumab) does increase bone density. Prolia works by targeting a molecule called RANKL that osteoclasts need to work. By stopping RANKL from binding to its receptor Prolia reduces bone breakdown, bone loss, bone pain, and other bone complications. BMD was increased by 8.8% at the lumbar spine, 6.4% at the total hip, and 5.2% at the femoral neck in trials that measured BMD after three years of treatment with Prolia. Continue reading
Evenity vs Prolia: Which is right for you?
Evenity (romosozumab-aqqg) and Prolia (denosumab) are two injectable medications that help lower the risk of bone fracture. When deciding which treatment option is best for you, it is important to consider factors such as who these medications are approved for, dosing, and side effects. Continue reading
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Drug information
- Prolia Information for Consumers
- Prolia prescribing info & package insert (for Health Professionals)
- Side Effects of Prolia (detailed)
- Prolia user reviews (374)
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