Why was Repatha Pushtronex discontinued and replaced?
Repatha Pushtronex was discontinued in order to uphold Amgen’s standards for patient experience and care. It was not discontinued because of safety or efficacy concerns. At this time, patients without homozygous familial hypercholesterolemia (HoFH) or a latex allergy should use the Repatha SureClick autoinjector. Patients with a latex allergy may use the new prefilled syringe that is not made with natural rubber latex.
When was the Repatha Pushtronex device discontinued?
Amgen stopped making the Repatha Pushtronex device on June 30, 2024.
What should I do with my Repatha Pushtronex device?
You can continue taking your medication as directed by your healthcare provider using your device. The manufacturer recommends speaking with your healthcare provider about transitioning to a different approved Repatha device, like the SureClick Autoinjector. It has less steps and takes less time to administer the medication compared with the Pushtronex system.
For questions about how to transition to a different Repatha device, contact your healthcare provider or Amgen SupportPlus at 1-844-REPATHA (1-844-737-2842), option 2. Hours: Monday-Friday 8:00 am - 8:00 pm ET.
References
Amgen. n.d. Repatha® Pushtronex® System (on-body-infusor with prefilled cartridge) Discontinuation. Accessed 03/08/2025 at https://www.repatha.com/~/media/12A733ED009842C68F1DA5F83532C636.ashx
Repatha.com. Important Notice for Patients: Discontinuation of Repatha®
(evolocumab) Pushtronex® System. Accessed 03/08/2025 at https://www.repatha.com/PushtronexSystemupdate
Repatha.com. How to Take Repatha. Accessed 03/08/2025 at https://www.repatha.com/how-to-start-repatha-injection
Read next
Are there any dangers of taking Repatha?
A serious danger of taking Repatha (evolocumab) includes a possibly life-threatening allergic reaction. Also tell your doctor if you are allergic to rubber or latex. Other side effects, which could be serious in some people, include high blood sugar levels (diabetes), respiratory tract infections, urinary tract infections (UTI), high blood pressure, and influenza (flu). Continue reading
Praluent vs Repatha: What's the difference?
The differences between Repatha (evolocumab) and Praluent (alirocumab) are their active ingredients, number of treatment indications, dosage forms available and number of strengths available in syringe and pens forms. Continue reading
What is the difference between Leqvio and Repatha?
Leqvio and Repatha are both injectable medicines that are used for the treatment of high cholesterol, by specifically lowering low density lipoprotein (LDL) levels. Although they both inhibit PCSK9 they work by different mechanisms. Repatha is a monoclonal antibody that binds directly to PCSK9 in the liver preventing it from binding to LDL receptors. Leqvio blocks the PCSK9 protein by interfering with the translation of PCSK9 messenger RNA. Both have the same result – and that is freeing up LDL receptors on the surface of liver cells which allows LDL cholesterol to be removed from the blood. Continue reading
Related medical questions
- What is the best time of day to take Repatha?
- How long can Repatha be kept unrefrigerated?
- Can Repatha cause high blood pressure?
- What are PCSK9 Inhibitors and how do they work?
- Does Repatha cause weight gain or loss?
- How do you inject Repatha?
- How much does Repatha cost?
- Can you drink alcohol and take Repatha?
- How does Repatha work?
- How long should you take Repatha?
- Is Repatha effective without a statin?
- How long do Repatha side effects last?
- How fast does Repatha work?
Drug information
Related support groups
- Repatha (34 questions, 102 members)
- Repatha Pushtronex (1 questions, 3 members)