When is the best time to take Aricept (donepezil)?

The manufacturer recommends taking Aricept (donepezil) in the evening just before bedtime. Aricept can cause nausea and vomiting in some patients, as well as dizziness. Taking it before bedtime may help these side effects be less noticeable. However, your prescriber might recommend taking Aricept at a different time if it’s interfering with your sleep. Take Aricept at the same time every day so the levels of medication stay consistent in your body.

What is Aricept used for?

Aricept is an acetylcholinesterase inhibitor that is FDA approved to treat dementia in patients with mild, moderate, and severe Alzheimer’s disease. It comes as a tablet and orally disintegrating tablet. Both dosage forms are available as brand-name and generic versions.

What is the typical dose of Aricept?

Aricept is available in 5 mg, 10 mg, and 23 mg strengths. The recommended starting dose is 5 mg by mouth once daily in the evening before bedtime. After 4-6 weeks, your healthcare provider might raise the dose to 10 mg once daily. In patients with moderate to severe Alzheimer’s disease, the dose may be raised to a maximum of 23 mg per day after taking the 10 mg dose for at least 3 months.

Aricept can be taken with or without food. The 23 mg tablet should not be crushed, and must be swallowed whole. If you are having trouble swallowing the tablet form, ask your healthcare provider about whether the orally disintegrating tablets are an option for you to take instead.