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What happens if you use an Epipen without needing it?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on Oct 31, 2024.

Official answer

by Drugs.com

The American College of Allergy, Asthma, and Immunology recommends using an EpiPen (generic name: epinephrine) even if you are not sure if it is needed, because the benefits greatly outweigh the risk that you might not need it.

While an EpiPen is a life-saving device for individuals with severe allergies, using it unnecessarily can lead to certain side effects. These side effects typically include:

  • Increased heart rate
  • Increased blood pressure
  • Headache
  • Tremors
  • Anxiety or nervousness

These side effects of using an EpiPen accidentally are usually temporary and less severe than the consequences of a severe allergic reaction. Some people with certain health problems might be at a higher risk for experiencing more severe side effects (e.g., abnormal heart rhythm, excess fluid in the lungs). Consult with a healthcare professional about when it is appropriate to use an EpiPen.

How soon will I feel the effects after using an EpiPen?

Studies of healthy adults not having an allergic reaction who took a dose of the EpiPen noticed effects 1 minute after using it. This is because unlike oral medication, it is injected directly into a muscle or under the skin.

What does an EpiPen do to a regular person?

If you accidentally use an EpiPen without needing it, your heart rate and blood pressure will go up within minutes. Other side effects you may experience include:

  • Anxiety
  • Restlessness
  • Tremor
  • Dizziness
  • Sweating
  • Headache

Additionally, your thigh might feel sore in the area where you injected the EpiPen. Get medical attention if you notice any side effects that seem severe.

Related questions

How long do side effects from EpiPen last?

Most side effects from a dose of EpiPen should go away within a few hours after using it. The effects of the medication typically start to wear off within 30 minutes. In a study of healthy adults who took a dose of the EpiPen, blood pressure returned to normal within 120 minutes. Pain where you injected the medication into your thigh should feel better within a few days.

If you believe you may be having a severe allergic reaction, it is essential to use your EpiPen immediately and seek emergency medical attention.

This is not all the information you need to know about EpiPen (epinephrine) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.

References

Allergy and Asthma Network. What is Epinephrine? Accessed 10/31/2024 at https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/

American College of Allergy, Asthma, and Immunology. 2018. Epinephrine Auto Injector. Accessed 10/31/24 at https://acaai.org/allergies/management-treatment/epinephrine-auto-injector/

Ellis, A. K., et. al. 2024. Development of neffy, an Epinephrine Nasal Spray, for Severe Allergic Reactions. Pharmaceutics. DOI: https://doi.org/10.3390/pharmaceutics16060811

EpiPen [package insert]. Updated February 2023. Mylan Specialty L.P. Accessed 10/31/24 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7560c201-9246-487c-a13b-6295db04274a

Read next

How and where is an Epipen injection given?

Epipen (epinephrine injection) is given as an intramuscular (in the muscle) or subcutaneous (under the skin) injection only in the middle of the outer side of the thigh (the upper leg). It can be injected through clothing if needed. Continue reading

Is Auvi-Q the same as EpiPen?

Auvi-Q is only available as a brand-name product, while EpiPen has generic versions available. They come in different dosages and sizes. Auvi-Q has voice instructions, while EpiPen does not. Continue reading

How much does Auvi-Q cost compared to EpiPen?

The cash price for a 2-pack of Auvi-Q autoinjector is around $300 compared to $650 for an EpiPen 2-pack. Prices can vary depending upon the pharmacy you visit and if you have any coupons or manufacturer discounts. Auvi-Q and EpiPen are brand names for epinephrine autoinjectors. Continue reading

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