What type of drug is Zejula?
Zejula (niraparib) is an oral, once-daily poly(ADP-ribose) polymerase inhibitor (PARP inhibitor).
PARP, or poly(ADP-ribose) polymerase, is a protein that helps repair damaged DNA. PARP inhibitors are targeted therapies that are used in the treatment of certain cancers.
PARP inhibitors work by stopping the repair of the damaged DNA in cancer cells, resulting in the death of the cancer cells.
Zejula was the third PARP Inhibitor to be approved by the FDA.
| PARP Inhibitor | Indications |
|---|---|
| Lynparza (olaparib) |
|
| Rubraca (rucaparib) |
|
| Zejula (niraparib) |
|
| Talzenna (talazoparib) |
|
Zejula is indicated:
- for the maintenance treatment of adult patients with advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to first-line platinum-based chemotherapy.
- for the maintenance treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.
Select patients for therapy based on an FDA-approved companion diagnostic for Zejula.
Related questions
- What type of cancer is Rubraca used to treat?
- What is the lifetime or cumulative dose for Adriamycin?
- Why give Taxol (Paxel) before carboplatin?
Read next
What is Paxel called in the USA?
Paxel contains the medicine paclitaxel, which was sold under the brand names Onxol and Taxol in the USA Continue reading
How long does it take Lynparza (olaparib) to work?
It takes Lynparza between two months and five months to start working depending on what cancer it is being used to treat. Continue reading
Anthracycline Drugs for Chemo: How Do They Work?
Anthracycline chemotherapy drugs are potent cancer treatments derived from Streptomyces bacteria. These drugs work by binding to cancer cell DNA, preventing replication and stopping tumor growth. Continue reading
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Botox
Botox is used cosmetically to reduce facial lines and wrinkles and for medical purposes for ...
Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Topamax
Topamax (topiramate) is used to prevent seizures in adults and children and to prevent migraine ...
Emgality
Emgality (galcanezumab-gnlm) is a CGRP antagonist for the preventive treatment of migraine and for ...
Timolol
Timolol is used for angina, heart attack, high blood pressure, migraine, migraine prevention
Valproic acid
Valproic acid is used for bipolar disorder, cluster-tic syndrome, epilepsy, headache ...
Divalproex sodium
Divalproex sodium is used for bipolar disorder, borderline personality disorder, cyclothymic ...
Propranolol
Propranolol is a beta-blocker that is used to treat tremors, chest pain, high blood pressure, heart ...
Related medical questions
- What are the long-term side effects of Adriamycin?
- How does carboplatin stop cancer?
- How effective is Lynparza (olaparib)?
- Does carboplatin cause neuropathy?
- What is the success rate of Elahere?
Drug information
- Zejula Information for Consumers
- Zejula prescribing info & package insert (for Health Professionals)
- Side Effects of Zejula (detailed)
- Zejula user reviews (58)
Related support groups
- Zejula (2 questions, 23 members)
- Ovarian Cancer (13 questions, 56 members)
- Fallopian Tube Cancer (3 questions, 4 members)
- Peritoneal Cancer (3 questions, 7 members)