Is Truxima a chemotherapy drug?
Truxima (rituximab-abbs) is not a chemotherapy drug, rather it is a biologic that is targeted toward specific antigens (proteins). In this case, Truxima targets the CD20 antigen expressed on the surface of pre-B and mature B-lymphocytes. Truxima forms a complex with the CD20 antigen which causes B-cell death (lysis). Most cases of non-Hodgkin’s lymphoma and chronic lymphocytic leukemia arise from B cells. Truxima is usually used together with chemotherapy treatments.
References
- Truxima (rituximab-abbs) Updated Feb 1, 2022 [Product Information] https://www.drugs.com/pro/truxima.html
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What are biosimilar drugs and how do they compare to biologics?
A biosimilar is a biological product that is similar to a reference biologic (usually the originally approved product) and for which there are no clinically meaningful differences in terms of safety, purity, and potency. One example is Amjevita (adalimumab-atto), the first biosimilar approved for Humira (adalimumab) in 2016.
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What is the difference between Truxima and Rituxan?
Truxima (rituximab-abbs) is a biosimilar to Rituxan (rituximab). While both drugs are CD20-directed cytolytic antibodies used to treat non-Hodgkin’s lymphoma (NHL), Rituxan has additional FDA-approved indications beyond NHL. Continue reading
Does Truxima make you gain weight?
Weight gain has been reported in 11% of patients being treated with Truxima (rituximab) for non-Hodgkin’s lymphoma (NHL). Be sure to contact your doctor right away if you have a rapid or unexplained weight gain or fluid retention (edema), nausea, vomiting, diarrhea, or lack of energy when using Truxima, as you may need immediate medical care. Continue reading
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Drug information
- Truxima Information for Consumers
- Truxima prescribing info & package insert (for Health Professionals)
- Side Effects of Truxima (detailed)
- Truxima user reviews (3)
Related support groups
- Truxima (5 questions, 4 members)
- Chronic Lymphocytic Leukemia (CLL) (27 questions, 57 members)
- Non-Hodgkin's Lymphoma (16 questions, 39 members)