Does Tezspire cause weight gain?
Weight gain is not a common side effect of Tezspire (tezepelumab-ekko). In two 52-week clinical trials, weight gain wasn’t reported as a side effect. Additionally, weight gain has not been reported in postmarketing monitoring.
Talk to your doctor if you have unexpected weight gain during your treatment with Tezspire. Gaining too much weight can lead to serious health problems, such as diabetes and heart disease.
Tezspire is a thymic stromal lymphopoietin (TSLP) blocker. It’s used for add-on maintenance treatment of severe asthma in adults and children 12 years and older. It is injected under the skin once a month. It was FDA approved in December 2021.
References
Corren, J., et. al. (2023). Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials. In: American Journal of Respiratory and Critical Care Medicine. Accessed on 05/31/24 at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10870853/
Tezspire [package insert]. (Revised May 2023). Amgen, Inc. Accessed 05/31/24 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=60f0aa03-ad25-4d48-80ce-7fcfa76f325f
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Drug information
- Tezspire Information for Consumers
- Tezspire prescribing info & package insert (for Health Professionals)
- Side Effects of Tezspire (detailed)
Related support groups
- Tezspire (3 questions, 4 members)
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