What is the strength of CaroSpir (spironolactone) oral suspension?
CaroSpir is an oral liquid suspension dosage form of the potassium-sparing diuretic spironolactone and comes in the strength of 25 milligrams (mg) per 5 milliliters (mL).
Spironolactone was first approved in tablet form under the brand name Aldactone in 1960. It is widely available as a generic.
CaroSpir was approved in 2017 as the first and only FDA-approved oral liquid dosage form of spironolactone. It provides a liquid treatment option for adult patients including those who have difficulty swallowing, or who cannot swallow tablets.
CaroSpir is indicated for:
- the treatment of NYHA Class III-IV heart failure and reduced ejection fraction to increase survival, manage edema, and to reduce the need for hospitalization for heart failure.
- use as an add-on therapy for the treatment of hypertension, to lower blood pressure.
- myocardial infarctions
- the management of edema in adult cirrhotic patients when edema is not responsive to fluid and sodium restrictions.
CaroSpir is not therapeutically equivalent to Aldactone or tablet forms of spironolactone. CaroSpir can produce 15 to 37% higher serum concentrations of spironolactone when compared to tablets.
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Winlevi vs Spironolactone: How do they compare?
Winlevi (clascoterone) and spironolactone are both prescribed to treat acne. Winlevi is a topical cream, while spironolactone is available in an oral tablet and oral suspension. Both Winlevi and spironolactone work well to treat acne by attaching to androgen receptors in the skin. Continue reading
How to increase ejection fraction naturally?
Lifestyle measures that can help improve your ejection fraction naturally, in addition to medications and other measures prescribed by your doctor, include doing moderate-intensity physical activity at least 3 to 5 times per week for at least 20 to 40 minutes per session, avoiding substances that can affect your heart or worsen your symptoms such as alcohol, cocaine, methamphetamines, stimulants, and cigarettes, limiting how much salt you eat to no more than 1,500 to 2,000 milligrams per day, manage your stress with relaxation exercises, meditation, yoga, and deep breathing. Continue reading
How can you check for heart disease at home?
You can check for heart disease at home by measuring your pulse rate and your blood pressure if you have a blood pressure monitor. To measure your pulse you will need an analog watch (one with a clock face rather than digital numbers) with a second hand. Place your index and middle finger of your hand on the hollow part of your inner wrist of the other arm, just below the base of the thumb. You should feel a tapping or pulse against your fingers, that is your heartbeat. Look at your watch and count the number of taps you feel in 10 seconds. Multiply that number by 6 to find out your heart rate for 1 minute. Continue reading
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Drug information
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