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Does Strattera give you energy like Adderall?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on July 30, 2024.

Official answer

by Drugs.com

Strattera (atomoxetine) can help improve your attention if you have attention deficit hyperactivity disorder (ADHD), which may make you feel like you have more energy. It is considered a nonstimulant medication, and it works differently than other ADHD medications. There have been reports of both drowsiness and trouble sleeping during clinical trials of Strattera in both children and adults.

Strattera differs from other ADHD medications in the way that it works in the brain. Specifically, it increases norepinephrine in the prefrontal cortex of the brain, but not in the mesocortical or mesolimbic regions. It also increases dopamine in the prefrontal cortex and does not affect reward-related areas of the brain. Some researchers believe this is one reason it has a low risk of abuse or dependence.

Does Strattera make you tired or awake?

Strattera can make you feel tired or more awake. During clinical studies, some patients with ADHD who took Strattera reported feeling tired or drowsy as a side effect. However, trouble sleeping was also commonly reported. This suggests Strattera could have either effect, and this will vary among individuals.

If you are experiencing significant tiredness or sleep disturbances while taking Strattera, talk to your healthcare provider.

References

Fu, D., et. al. 2021. The Mechanism, Clinical Efficacy, Safety, and Dosage Regimen of Atomoxetine for ADHD Therapy in Children: A Narrative Review. In: Frontiers in Psychiatry. DOI: https://doi.org/10.3389/fpsyt.2021.780921

Santos de Silva, B., et. al. 2023. An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder. In: Discover Mental Health. DOI: https://doi.org/10.1007%2Fs44192-022-00030-1

Strattera [package insert]. Updated January 2022. Eli Lilly and Company. Accessed 07/28/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=309de576-c318-404a-bc15-660c2b1876fb

Read next

How long does it take for Strattera to work?

Strattera starts to work for attention-deficit hyperactivity disorder (ADHD) as soon as the first day of taking a dose. However, it can take 8-12 weeks for its full effects to be reached. Some people may continue to notice an increased response for up to 24 weeks or longer. Continue reading

Strattera vs Adderall: What is the difference?

Strattera contains atomoxetine whereas Adderall contains a mixture of amphetamine salts (MAS). Both Strattera and Adderall are effective for ADHD; however, Strattera is not a stimulant which means it is not likely to be abused or cause dependence, tolerance, or withdrawal symptoms on discontinuation. Continue reading

What are the benefits of taking Strattera at night?

Research has shown Strattera works just as well whether it’s taken once a day in the morning or twice a day (morning and evening). Symptom improvement lasts for 24 hours, regardless of what time it is taken. This allows patients and their healthcare providers to be flexible on a dosing schedule that works for them. Continue reading

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