Does Stelara cause hair loss?
No, Stelara (ustekinumab) has not been shown to commonly cause hair loss in clinical studies.
What Is Stelara Used For?
Stelara is prescribed for the treatment of:
- Moderate to severe plaque psoriasis and active psoriatic arthritis (adults and children 6 years and older).
- Moderately to severely active Crohn’s disease (CD) and ulcerative colitis (adults).
Stelara and Hair Loss
Hair loss was not commonly reported during clinical trials. In phase 3 clinical studies of Stelara in adults with CD and UC, about 1% of patients reported hair loss (alopecia) as a side effect compared to 2.6% of patients taking a placebo.
A 2017 case study in the Journal of The American Academy of Dermatology showed that hair loss caused by the autoimmune disorder alopecia areata, which can be a concurrent condition to patients with psoriasis, responded well to Stelara. Researchers noted an increase in hair density, though larger studies are are needed to confirm this effect.
Common Side Effects of Stelara
Common side effects of Stelara include:
- Diarrhea
- Vomiting
- Fever
- Abdominal pain, back pain
- Headache
- Upper respiratory tract infection, nasopharyngitis
- Headache
- Dizziness
- Itching (pruritus)
- Depression, fatigue
- Weight loss
- Rectal bleeding
Conclusion
Stelara has not been linked to hair loss, and some reports suggest it may even benefit patients with alopecia areata. If you experience hair loss while taking Stelara, consult your healthcare provider to explore potential causes and treatment options.
References
- U.S Food and Drug Administration (FDA). Stelara. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/761044s010lbl.pdf [Accessed August 2, 2022]
- Janssen Biotech, Inc. Stelara:Important safety information. Available at: https://www.stelarainfo.com/safety [Accessed June 9, 2022]
- Elkady A, Bonomo L, Amir Y, Vekaria AS, Guttman-Yassky E. Effective use of ustekinumab in a patient with concomitant psoriasis, vitiligo, and alopecia areata. JAAD Case Rep. 2017;3(6):477-479. doi:10.1016/j.jdcr.2017.07.009. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614637/
- J&J Medical Connect. 2025. Occurrence of Alopecia in Adult Patients with Crohn's Disease or Ulcerative Colitis Treated with STELARA. Accessed on March 26, 2025 at https://www.jnjmedicalconnect.com/products/stelara/medical-content/occurrence-of-alopecia-in-adult-patients-with-crohns-disease-or-ulcerative-colitis-treated-with-stel
Read next
What are 7 key Stelara side effects to watch out for?
Common side effects of Stelara include nasopharyngitis, infections, nausea, and injection site reactions. More serious but rare side effects of Stelara are severe allergic reactions, posterior reversible encephalopathy syndrome (PRES), and a potentially higher risk of cancer. Continue reading
What food should I avoid while on Stelara?
There are no known food interactions with Stelara (ustekinumab). However, potential interactions have not been fully studied, so consult your doctor about any necessary dietary adjustments. Stelara is a biologic medication that suppresses parts of the immune system, increasing the risk of infections. For this reason, food safety is critical. Continue reading
Stelara and the Covid Vaccine: What should I know?
While there is limited data on how Stelara specifically affects the COVID-19 vaccine, all non-live vaccines, including COVID-19 vaccines, are generally considered safe for Stelara patients. Continue reading
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Drug information
- Stelara Information for Consumers
- Stelara prescribing info & package insert (for Health Professionals)
- Side Effects of Stelara (detailed)
- Stelara user reviews (252)
Related support groups
- Stelara (24 questions, 68 members)