Is Stelara a biologic?
Yes, Stelara (ustekinumab) is a biologic medication. Biologics, also known as a biopharmaceuticals, are drugs made from naturally occurring molecules, such as proteins, genes, antibodies, sugars, tissues, or cells.
How Does Stelara Work?
Stelara is a monoclonal antibody designed to reduce inflammation by blocking two immune system proteins, interleukin-12 (IL-12) and interleukin-23 (IL-23). These proteins contribute to inflammatory diseases by triggering an overactive immune response. By targeting IL-12 and IL-23, Stelara helps regulate the immune system and decrease inflammation.
What Conditions Does Stelara Treat?
Stelara is prescribed to treat
These conditions are caused by excessive immune system activity, leading to chronic inflammation. By blocking key inflammatory proteins, Stelara helps manage symptoms and improve patient outcomes.
References
- Janssen. Stelara. Available at: https://www.stelarainfo.com/crohns-disease/about-stelara#slide-1 [Accessed June 12, 2022]
- U.S Food and Drug Administration. Stelara. September 23, 2016. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/nda/2016/761044Orig1s000SumR.pdf [Accessed June 12, 2022]
- U.S. Food & Drug Administration. What are “biologics” questions and answers. Feb. 6, 2018. Available at: https://www.fda.gov/about-fda/center-biologics-evaluation-and-research-cber/what-are-biologics-questions-and-answers [Accessed June 12, 2022]
Read next
What are 7 key Stelara side effects to watch out for?
Common side effects of Stelara include nasopharyngitis, infections, nausea, and injection site reactions. More serious but rare side effects of Stelara are severe allergic reactions, posterior reversible encephalopathy syndrome (PRES), and a potentially higher risk of cancer. Continue reading
What food should I avoid while on Stelara?
There are no known food interactions with Stelara (ustekinumab). However, potential interactions have not been fully studied, so consult your doctor about any necessary dietary adjustments. Stelara is a biologic medication that suppresses parts of the immune system, increasing the risk of infections. For this reason, food safety is critical. Continue reading
Stelara and the Covid Vaccine: What should I know?
While there is limited data on how Stelara specifically affects the COVID-19 vaccine, all non-live vaccines, including COVID-19 vaccines, are generally considered safe for Stelara patients. Continue reading
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Drug information
- Stelara Information for Consumers
- Stelara prescribing info & package insert (for Health Professionals)
- Side Effects of Stelara (detailed)
- Stelara user reviews (252)
Related support groups
- Stelara (24 questions, 68 members)