Does Rituxan cause hair loss?

Hair loss is a possible side effect of Rituxan (rituximab), though it is not common. If hair loss occurs, it may affect the scalp, eyebrows, eyelashes, or body hair. Some people experience patchy hair loss or thinning, but in most cases, hair grows back after completing treatment.

How Common Is Hair Loss With Rituxan?

Hair loss (alopecia) does not seem to be a common side effect of Rituxan. Hair loss was rarely reported as a side effect in a systematic review and meta-analysis of Rituxan studies.

In a small clinical study of patients taking Rituxan for pemphigus vulgaris, 13% of patients taking Rituxan together with prednisone reported hair loss as a side effect. This was compared to 0% of patients taking prednisone alone. Hair loss was not commonly reported in studies of patients taking Rituxan for other health conditions.

FDA Reports

As of March 2024, the FDA Adverse Events Reporting System recorded 1,656 reports of hair loss in Rituxan users. However, these reports do not always confirm Rituxan as the cause, as patients may be taking other medications or have unrelated conditions.

What Should I Do If I Experience Hair Loss on Rituxan?

If you notice hair thinning or loss while taking Rituxan, speak with your healthcare provider. They can help determine the cause and suggest management strategies.