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How are Opdivo and Yervoy administered?

Medically reviewed by Carmen Pope, BPharm. Last updated on Jan 21, 2025.

Official answer

by Drugs.com

Opdivo and Yervoy are administered by slow intravenous infusion over at least 30 minutes – this is when a bag containing the medicine is hung from a stand, and the medicine runs through a piece of tubing called an intravenous line into your vein. This needs to be done in your healthcare provider’s office, an infusion center, or a hospital.

Opdivo and Yervoy are often administered in combination for the first dose for conditions such as non-small cell lung cancer, melanoma, and advanced kidney cancer, but each infusion is administered separately, and each takes at least 30 minutes to administer. Opdivo and Yervoy are not mixed in the same bag.

Once your combination treatment with Opdivo and Yervoy has finished, your healthcare provider my decide to start you on Opdivo Qvantig for maintenance treatment. This is given as an injection under the skin over 3 to 5 minutes.

References

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How effective is Opdivo?

The effectiveness of Opdivo at prolonging or extending life depends on the type and stage of cancer it is used to treat and if it is used alone or in combination with other treatments (such as Yervoy). There are several ways clinical trials measure success. Continue reading

How long does Opdivo take to work and how do you know if it's working?

Results from clinical trial indicate that it can take about 2 months to see a response to treatment with Opdivo, but some patients will respond more quickly and others will take longer.

Your doctor will order periodic tests, such as CT (computed tomography) and PET (positron emission tomography) scans and MRI (magnetic resonance imaging) to see if you are responding to treatment. Continue reading

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