Skip to main content

How long does it take for Lexapro to work?

Medically reviewed by Carmen Pope, BPharm. Last updated on Nov 25, 2024.

Official answer

by Drugs.com

Even though it takes Lexapro only a few hours to increase serotonin levels within the brain, it may take several weeks to start working. Signs that Lexapro has started working include an improvement in your sleep, energy, or appetite. In some, this may happen in as little as 1 to 2 weeks. Relief from symptoms, such as a depressed mood or a lack of interest in activities you used to enjoy, may take up to 6 to 8 weeks to fully improve.

How long can you take Lexapro?

If this is your first episode of depression, your doctor may prescribe Lexapro for a set period, for example, 6 months to a year. Some people with persistent depression may need to take it for many years. There are no known problems when Lexapro is taken long-term.

References
  • Escitalopram (Lexapro) National Alliance on Mental Illness (NAMI).https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Types-of-Medication/Escitalopram-(Lexapro)
  • Lexapro (escitalopram oxalate). Updated 09/2021. Allergan, Inc. https://www.drugs.com/pro/lexapro.html

Read next

Why does Lexapro cause weight gain?

Lexapro may cause weight gain because it blocks the serotonin transporter, which increases levels of serotonin in the brain, but also increases appetite and decreases metabolism. Research has shown approximately 40% of people taking antidepressants such as Lexapro will gain 7% or more of their starting body weight. The weight gain experienced with Lexapro is a lot less than that reported with other antidepressants such as paroxetine, mirtazapine, or doxepin but more than fluoxetine. Continue reading

When is the best time to take Lexapro?

Lexapro is usually taken once a day and you can take it either in the morning or at night. Continue reading

Does Lexapro cause night sweats?

Lexapro can cause night sweats and increased sweating overall (night and day) was one of the most common side effects reported with Lexapro, reported by 3% to 8% (depending on the dose) of people. Although night sweats can be worrisome, they usually diminish with time as your body and brain adjust to the medication. Continue reading

Related medical questions

Drug information

Related support groups