Does Humira make you feel tired?

Fatigue is not a common side effect of Humira (adalimumab). However, if you feel unusually tired, it could be a sign of an underlying issue, such as:

• Infection – Humira weakens the immune system, increasing infection risk.
• Liver problems – Though rare, Humira may affect liver function, which can cause fatigue.

Additionally, Humira is used to treat conditions that themselves can cause fatigue, such as rheumatoid arthritis, Crohn's disease, and ulcerative colitis.

Common Side Effects of Humira

The most common side effects of Humira are:

• Infections (e.g., colds, sinus infections)
• Injection site reactions (redness, swelling, pain)
• Headache
• Rash

If you experience persistent or bothersome symptoms, speak with your healthcare provider.

What Conditions Does Humira Treat?

Humira is the brand name for the medication adalimumab. It is approved for several autoimmune diseases, including:

• Ankylosing Spondylitis
• Crohn's disease
• Juvenile idiopathic arthritis
• Plaque Psoriasis
• Psoriatic arthritis
• Rheumatoid arthritis
• Ulcerative colitis
• Uveitis

It is also FDA approved to treat a chronic inflammatory skin condition called hidradenitis suppurativa.

When to Contact Your Doctor

If fatigue is severe, persistent, or accompanied by other symptoms like fever, yellowing skin, or dark urine, contact your healthcare provider immediately.