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How long can you take Celebrex for?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on Feb 14, 2025.

Official answer

by Drugs.com

The length of time you can take Celebrex (celecoxib) depends on your specific condition and your doctor's recommendation. The manufacturer recommends to use the lowest possible dosage that is effective for your symptoms for the shortest amount of time needed.

While Celebrex can be used for both short-term and long-term treatment, it's crucial to follow your doctor's advice to minimize potential side effects. Taking Celebrex for a long period of time may put you at a higher risk for side effects.

What is Celebrex used for?

Celebrex is a nonsteroidal anti-inflammatory drug (NSAID) that is FDA approved to treat the following:

  • Acute pain
  • Ankylosing spondylitis
  • Juvenile rheumatoid arthritis
  • Osteoarthritis
  • Primary dysmenorrhea
  • Rheumatoid arthritis

For some conditions, you may only need to take Celebrex for a short period of time (days to weeks). Your healthcare provider might prescribe longer courses for chronic conditions such as arthritis. If you are not sure how long you should take this medication, ask your healthcare provider.

What are side effects of Celebrex?

Common side effects reported by people taking Celebrex in clinical trials include:

  • Stomach pain
  • Diarrhea
  • Indigestion
  • Gas
  • Swelling in the arms and legs
  • Upper respiratory tract infection

Additionally, Celebrex can raise your risk of more rare but serious side effects, including:

  • Blood clots
  • Heart attack
  • Stroke
  • Stomach bleeding
  • Ulcers
  • Liver damage
  • High blood pressure
  • Worsening of heart failure
  • Kidney damage
  • Serious allergic or skin reaction

These are not all possible side effects of Celebrex. Follow up with your healthcare provider to learn more.

Related questions

How long does Celebrex stay in your system?

In adults, Celebrex typically stays in the body for about 2-3 days. This is based on the half-life of the medication, which is a measure of the amount of time until half of the medication is cleared from your system. The half-life of Celebrex is 11.2 hours. It takes about five half-lives for the medication to be considered fully out of your system. It could take longer for Celebrex to leave your system if you have liver problems, since this could cause the medication to break down more slowly.

In children, it takes about 1-2 days for Celebrex to leave the system. This is because the half-life in children is shorter, meaning it is cleared more quickly from the body.

This is not all the information you need to know about Celebrex (celecoxib) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.

References

Celebrex [package insert]. 2024. Viatris Specialty LLC. Accessed 11/07/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d6675e4-5859-4be2-8037-a20ce9f707aa

Cure, M. C., et. al. 2020. NSAIDs may increase the risk of thrombosis and acute renal failure in patients with COVID-19 infection. In: Elsevier Therapie. DOI: https://doi.org/10.1016/j.therap.2020.06.012

Ungprasert, P., et. al. 2014. Non-steroidal anti-inflammatory drugs and risk of venous thromboembolism: a systematic review and meta-analysis. In: Rheumatology. DOI: https://doi.org/10.1093/rheumatology/keu408

UpToDate. Celecoxib drug information. Accessed 11/07/2024 at https://www.uptodate.com/contents/celecoxib-drug-information

Read next

Is meloxicam very similar to Celebrex?

At lower doses, meloxicam is more similar to Celebrex (celecoxib) than it is to other NSAIDs, like ibuprofen or naproxen, because it is relatively selective for the COX-2 enzyme. But at higher doses, even within the prescribed range, meloxicam can inhibit both COX-1 and COX-2 enzymes, which may lead to side effects like stomach ulcers or bleeding. COX-2 selectivity is a dose-related effect. Continue reading

Does Celebrex act as a blood thinner or cause bleeding?

No, Celebrex (celecoxib) does not act as a blood thinner. This is because it selectively inhibits cyclooxygenase-2 (COX-2) and not COX-1. Continue reading

Can I take Celebrex if I have a sulfa allergy?

Celebrex (celecoxib) contains a sulfonamide group that is chemically related to sulfa drugs, so people with a sulfa allergy should be cautious when taking it. However, evidence for cross-reactivity among different sulfonamide medications is inconsistent, and you should talk to your healthcare provider about this because it may depend on factors such as the severity of your sulfa allergy. Continue reading

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