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How long does it take Rystiggo to work?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on March 31, 2025.

Official Answer by Drugs.com

Rystiggo (rozanolixizumab) may start working within one week of the first dose. In a clinical trial, patients saw improvements in daily activities affected by generalized myasthenia gravis (gMG) by the end of six weeks of treatment.

However, individual responses vary, and not everyone will experience symptom improvement. If you have concerns about your progress, discuss them with your healthcare provider.

How Does Rystiggo Work?

Rystiggo is a monoclonal antibody that targets the neonatal Fc receptor (FcRn). By blocking FcRn, Rystiggo helps reduce immunoglobulin G (IgG) autoantibodies, which are proteins that mistakenly attack the body's own cells.

This reduction in IgG autoantibodies can help restore acetylcholine signaling between nerves and muscles, potentially leading to improved muscle strength.

References

Rystiggo (rozanolixizumab-noli). FAQs. Accessed July 24, 2024 at https://www.rystiggo.com/faq

Rystiggo (package insert). Updated June 2024. UCB, Inc. Accessed July 24, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3c0eb8c2-c042-4954-b451-3baa77f5e6d1

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