How long does it take for Aricept to work?
Aricept (donepezil) may start working within 3 weeks of starting treatment to improve Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-cog) scores, but can take up to 4-6 weeks to be effective for some people. The ADAS-cog test measures performance on language and memory to help determine the extent of cognitive impairment.
How do I know if donepezil is working?
As Aricept begins to work, you may remember things easier and be able to concentrate better. It might also become easier to manage daily activities such as bathing, dressing, and eating. Aricept is not a cure for Alzheimer’s disease, and only provides modest benefits.
Not everyone responds to Aricept the same way. Some patients might experience significant improvements in their symptoms, while others might only see mild benefits or no improvement at all. If you haven’t noticed an improvement in your symptoms after taking Aricept for 4-6 weeks, let your doctor know. They might be able to raise your dose to see if that helps, or recommend a different treatment option.
References
Aricept [package insert]. (Updated Dec 2021). Eisai Inc. Accessed 07/12/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=98e451e1-e4d7-4439-a675-c5457ba20975
Birks, J. S., et. al. (2018). Donepezil for dementia due to Alzheimer's disease. DOI: https://doi.org/10.1002%2F14651858.CD001190.pub3
National Health Services. (Updated March 2023). Common questions about donepezil. Accessed 07/12/2024 at https://www.nhs.uk/medicines/donepezil/common-questions-about-donepezil/
Rockwood, K., et. al. (2007). The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial. In: BMC Neurology. DOI: https://doi.org/10.1186%2F1471-2377-7-26
Read next
Related medical questions
- Can Aricept be stopped abruptly?
- What are the current medications for Alzheimer's disease?
- What is Quercetin and what are its health benefits?
- What's the mechanism of action for Leqembi (lecanemab-irmb)?
- How does Namenda work?
- What are 4 key Namenda side effects to watch out for?
- Is Razadyne (galantamine) used to treat Alzheimer’s?
- Is Leqembi used to treat Alzheimer's?
- Caring for a Senior with Dementia
Drug information
- Aricept Information for Consumers
- Aricept prescribing info & package insert (for Health Professionals)
- Side Effects of Aricept (detailed)
Related support groups
- Aricept (11 questions, 43 members)
- Alzheimer's Disease (25 questions, 97 members)