How long does Flexeril stay in your system?
Medically reviewed by Drugs.com. Last updated on April 7, 2025.
As an estimate, after taking a dose of Flexeril it should be out of your system within 5.5 days to 16.5 days.
Flexeril has a long half life of between 1 and 3 days. This is the time it takes for your body to reduce the plasma drug levels by half. Flexeril is eliminated slowly from the body. It usually takes around 5.5 x half-life for a drug to be eliminated from your system. This is (5.5 x 1) 5.5 days to (5.5 x 3) 16.5 days for Flexeril.
However other factors to consider include:
1. How much and how often you have taken the drug.
2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
4. Body mass – generally the bigger you are the longer a drug will remain in your system.
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Topamax
Topamax (topiramate) is used to prevent seizures in adults and children and to prevent migraine ...
Emgality
Emgality (galcanezumab-gnlm) is a CGRP antagonist for the preventive treatment of migraine and for ...
Timolol
Timolol is used for angina, heart attack, high blood pressure, migraine, migraine prevention
Valproic acid
Valproic acid is used for bipolar disorder, cluster-tic syndrome, epilepsy, headache ...
Divalproex sodium
Divalproex sodium is used for bipolar disorder, borderline personality disorder, cyclothymic ...
Topiramate
Learn about topiramate, an anticonvulsant used for seizures, migraine prevention, and weight loss ...
Related medical questions
- How much cyclobenzaprine can I take?
- How long does it take for Flexeril to work?
- Is cyclobenzaprine a controlled substance or addictive?
- Can I take cyclobenzaprine and Tylenol together?
- Is Flexeril addictive, will it show up on a drug test?
- How do I treat back pain without using opioids?
Drug information
Related support groups
- Cyclobenzaprine (73 questions, 125 members)
- Flexeril (80 questions, 159 members)