What causes hepatitis C - how do you get or catch it?
What causes HCV?
Hepatitis C virus (HCV) is a liver infection you can catch when the blood of an infected person enters your bloodstream. You can get HCV by:
- sharing drug injection equipment such as needles or syringes
- being born to a mother with HCV
- having an accidental needle stick (such as a healthcare worker)
- sharing personal items contaminated with HCV+ blood like nail clippers, razors or toothbrushes (or other items that may have come into contact with infected blood)
- receive a tattoo or body piercing using unsterile equipment (unregulated facilities may be a higher risk)
- receiving hemodialysis
- receiving a blood transfusion or organ transplant before 1992 (this risk now is extremely low) or received clotting factor concentrates before 1987
- having unprotected sex with an infected person, especially for men who have sex with men
- an exposure from a healthcare worker, although this is uncommon
Hepatitis C is not spread through food or water. You also don't get it from sharing food utensils, breastfeeding your baby, kissing, hugging, holding hands, coughing or sneezing.
Related: Medications Used to Treat Hepatitis C
How do I know if I have hepatitis C virus (HCV)?
Diagnosis of hepatitis C virus requires a blood test your doctor can order. Other blood tests can determine which subtype of HCV you have to better target your drug treatment, if needed. Your doctor will also want to know your viral load (the quantity of the hepatitis C virus in your blood). In some patients, a liver biopsy is required to determine the level of damage.
Symptoms of chronic (long-term) HCV may not appear for 2 to 3 decades after infection, so the disease may develop silently in your body for many years. This is the reason you should be tested for HCV infection, to start treatment if needed and to help protect your liver from damage.
The US Centers for Disease Control and Prevention (CDC) recommends anyone 18 years or older be tested for hepatitis C virus at least once in their lifetime. Women should be tested for hepatitis C testing during each pregnancy. Some high risk groups may need more frequent testing, such as people who share drug preparation equipment and those on hemodialysis.
Learn More: Oral Hepatitis C Treatments: The Evolving Landscape
Related questions
- What types of Hepatitis C does Mavyret treat?
- What types of hepatitis C (HCV) does Vosevi treat?
- What type of Hepatitis C is Zepatier used to treat?
How do the symptoms of acute vs. chronic HCV differ?
Most people who have newly acquired HCV do not develop acute symptoms right after infection. However, some people may develop symptoms after 2 to 12 weeks, which can last 1 to 3 months, such as:
- yellow-colored skin or eye sclera (jaundice)
- weakness or muscle aches
- fatigue
- poor appetite
- nausea, vomiting and stomach pain
Longer-term (chronic) symptoms may include:
- weight loss
- poor appetite
- nausea or vomiting
- feeling tired
- fever
- painful joints
- dark-colored urine
- clay-colored (light) bowel movements
- jaundice (yellow skin or eyes) and itchy skin
- pain in the right upper side of your stomach area
Chronic (long-term) hepatitis C can cause serious health problems, including liver damage, cirrhosis (scarring of the liver), liver cancer, and even death. If you eventually develop cirrhosis (a scarring disease of the liver), symptoms may include stomach swelling, easy bruising, trouble breathing, jaundice, and confusion.
References
- FAQs about Sustained Virologic Response to Treatment for Hepatitis C. July 2020. US Departments of Veterans Affairs. Accessed July 8, 2021 at https://www.hepatitis.va.gov/pdf/sustained-virological-response.pdf
- Schillie S, Wester C, Osborne M, et al. CDC Recommendations for Hepatitis C Screening Among Adults — United States, 2020. MMWR Recomm Rep 2020;69(No. RR-2):1–17. Accessed July 8, 2021 at DOI: http://dx.doi.org/10.15585/mmwr.rr6902a1
- Hepatitis C Basics. Centers for Disease Control and Prevention (CDC). May 30, 2024. Accessed Oct 23, 2024 at https://www.cdc.gov/hepatitis-c/about/
Read next
What is the difference between hepatitis B and C?
Some of the main differences between hepatitis B and C are:
- Hepatitis B virus can be prevented with a vaccine, but not hepatitis C.
- Hepatitis B and C are different viruses, but you can have both hepatitis B and hepatitis C at the same time.
- Over 90% of people infected with hepatitis C who have not received treatment can be cured with 8 to 12 weeks of oral medications, but treatment for hepatitis B, if needed, may be long-term or lifelong.
- There is no cure for hepatitis B, but once you recover from acute hepatitis B, you develop antibodies that protect you from the virus for life.
What are the new drugs for the treatment of hepatitis C?
The newest drugs for the treatment of hepatitis C include Mavyret (glecaprevir and pibrentasvir), Vosevi (sofosbuvir, velpatasvir, and voxilaprevir), and Epclusa (sofosbuvir and velpatasvir). All are FDA-approved for the treatment of chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis (Child-Pugh A), as well as other uses. Continue reading
Why there is no vaccine for hepatitis C?
- Bailey JR, Barnes E, Cox AL. Approaches, Progress, and Challenges to Hepatitis C Vaccine Development. Gastroenterology. 2019 Jan;156(2):418-430. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340767/
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Hepatitis C. March 2020. Available at: https://www.niddk.nih.gov/health-information/liver-disease/viral-hepatitis/hepatitis-c [Accessed August 10, 2021].
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