Does Gemtesa (vibegron) cause weight gain?
Weight gain is not listed as a side effect of Gemtesa (vibegron) in the product information and there does not seem to be any anecdotal reports of weight gain from blog sites or Gemtesa reviews. Gemtesa does not cause weight gain.
It is possible that beta-3 agonists, such as Gemtesa, could promote weight loss. A small study that investigated mirabegron, another beta-3 agonists used for OAB, found that it also activated beta-3 receptors located in brown fat (adipose) tissue which boosted the participants' ability to burn energy, increasing the number of calories they burned. But this was a preliminary study and larger trials are needed.
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Can Gemtesa cause dementia?
Cognitive decline, which may include dementia, memory loss and confusion, is not a known side effect for Gemtesa (vibegron) or the beta-3 agonist class as a whole. In addition, a study found the use of anticholinergic medications among patients with overactive bladder (OAB) was associated with an increased risk of new-onset dementia compared to beta-3 agonist users. Continue reading
How long does it take for Gemtesa (vibegron) to work?
Gemtesa (vibegron) starts working almost immediately – within a few days of first taking it, with noticeable improvements in urinary urgency, frequency, and incontinence noted in clinical trials at 2 weeks which were reported as significant by 12 weeks.
After 12 weeks, people taking Gemtesa had 2 fewer daily leakage episodes compared to 1 fewer episode in those taking placebo, 2 fewer bathroom visits (versus 1 fewer with placebo), and 3 fewer “urge to go” visits a day compared to 2 fewer with placebo. Continue reading
Does Gemtesa cause high blood pressure?
No, it isn’t common for Gemtesa (vibegron) to cause high blood pressure. In the phase 3 EMPOWUR trial of patients taking 75 mg of Gemtesa per day, Gemtesa had low rates of high blood pressure (1.7%) that were similar to placebo. Continue reading
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Drug information
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