Does Gemtesa cause high blood pressure?
No, it isn’t common for Gemtesa (vibegron) to cause high blood pressure.
In the phase 3 EMPOWUR trial of patients taking 75 mg of Gemtesa per day, Gemtesa had low rates of high blood pressure (1.7%) that were similar to placebo. Additionally, a 4-week study showed that patients who took a daily dose of 75 mg of Gemtesa did not experience significant changes in blood pressure.
Talk to your doctor if you notice an increase in your blood pressure. High blood pressure can put you at a higher risk for serious medical problems, such as heart failure, stroke, and kidney damage.
Gemtesa is a beta-3 adrenergic agonist used to treat overactive bladder. It is typically taken by mouth once a day. Some potential side effects include headache, urinary tract infection, and diarrhea.
References
Gemtesa [package insert]. (Revised Feb 2024). Sumitomo Pharma America, Inc. Accessed 06/15/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25f21d25-14f8-4fda-91f6-7aa8b68aa1c8
Staskin, D., et. al. (2020). International Phase III, Randomized, Double-Blind, Placebo and Active Controlled Study to Evaluate the Safety and Efficacy of Vibegron in Patients with Symptoms of Overactive Bladder: EMPOWUR. In: The Journal of Urology. Available from: https://www.auajournals.org/doi/10.1097/JU.0000000000000807
Weber, M. A., et. al. (2022). Effects of vibegron on ambulatory blood pressure in patients with overactive bladder: results from a double-blind, placebo-controlled trial. In: Blood Pressure Monitor. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893125/
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Drug information
- Gemtesa Information for Consumers
- Gemtesa prescribing info & package insert (for Health Professionals)
- Side Effects of Gemtesa (detailed)
Related support groups
- Gemtesa (10 questions, 12 members)
- High Blood Pressure (484 questions, 1,603 members)
- Overactive Bladder (37 questions, 178 members)