How does Evenity work?
Evenity (romosozumab-aqqg) is a humanized monoclonal antibody that works by inhibiting the activity of sclerostin, which is a small protein found in osteocytes. It increases bone formation and reduces bone loss.
Evenity was approved in April 2019 for postmenopausal women at high risk of fracture and is given by injection by a healthcare provider once a month for a treatment period of 12 months. After the 12-month course, therapy should continue with an anti-resorptive agent.
The main side effects associated with Evenity are joint pain (arthralgia) and headache. Evenity can also increase a woman's risk of having a heart attack and stroke, and for this reason, it carries a boxed warning, and should not be given to women with other cardiovascular risk factors.
Read next
Evenity vs Prolia: Which is right for you?
Evenity (romosozumab-aqqg) and Prolia (denosumab) are two injectable medications that help lower the risk of bone fracture. When deciding which treatment option is best for you, it is important to consider factors such as who these medications are approved for, dosing, and side effects. Continue reading
What happens when you stop Evenity?
Within months of stopping Evenity (romosozumab), its effects on bone formation and resorption will diminish. Studies suggest that if you stop taking Evenity after three months, it can stay in the body for about 2 months. However, it can take up to 12 months for P1NP and CTX levels to return to what they were before you started treatment. Continue reading
Does Evenity cause dental problems?
Evenity (romosozumab) can rarely cause osteonecrosis of the jaw (ONJ), a rare but serious side effect. This condition occurs when there is loss of blood supply to the jaw. As a result, the jawbone is exposed and bone cells die. Continue reading
Related medical questions
- What is the billing J Code for Evenity?
- What medications are available to treat osteoporosis?
- What are the side effects of Vitamin D?
- What's the difference between osteoporosis, osteopenia and osteoarthritis?
- What is the connection between the endocrine system and osteoporosis?
- How does teriparatide (Forteo) work?
- What are the ICD-10 codes for osteoporosis?
- Are there any natural treatments for osteoporosis?
- How can I prevent osteoporosis?
- What is the best diet or foods to help with osteoporosis?
- Osteoporosis FAQs: Your Top Questions Answered
- Is osteoporosis hereditary?
- How does resistance training prevent osteoporosis?
- What exercises are good for osteoporosis?
- What are the risk factors for osteoporosis?
- What causes osteoporosis?
- How many years should you take Prolia?
- What's the difference between Prolia and Reclast?
- How do you give a Prolia injection?
- Xgeva vs Prolia. How do they compare?
- Insights from a Pharmacist about Osteoporosis Treatments
- Can Tymlos cause bone cancer?
- How does Evista (raloxifene) work?
- How do you use Tymlos?
- How does food interact with your medications?
- Hot Flashes, Mood Swings... wait... could this be Menopause?
- Using Dietary Supplements Wisely
Drug information
Related support groups
- Evenity (6 questions, 6 members)
- Romosozumab (1 questions, 3 members)
- Osteoporosis (69 questions, 293 members)