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Is Entyvio used to treat Crohn’s disease?

Medically reviewed by Carmen Pope, BPharm. Last updated on May 16, 2024.

Official answer

by Drugs.com

Entyvio (vedolizumab) may be used to treat moderately to severely active Crohn's disease (CD) in adults. It helps to control inflammation in the gut when other medications for CD have not worked well enough or have side effects that are difficult for the person with CD to tolerate.

In patients with Crohn’s disease, 15% of those receiving Entyvio in 2 studies were in remission at 6 weeks, compared to 7% and 12% on placebo. Only one study was found to be statistically significant.

In a follow-up study of people who had previously responded to Entyvio in a previous trial, 39% were in clinical remission at week 52 and 44% had a clinical response by week 52. Of those who had previously been prescribed corticosteroids, 32% were now corticosteroid-free.

Individual results may vary. Not every patient will respond to Entyvio. Entyvio is usually administered through an intravenous (IV) infusion by a healthcare provider for the first 2 doses, and as a subcutaneous (SC) (under the skin) injection for subsequent doses that you can self-administer at home using a prefilled pen or syringe.

References
  • Entyvio (vedolizumab) Injection. Updated 05/2024. Takeda Pharmaceuticals America, Inc. https://www.drugs.com/pro/entyvio-injection.html

Read next

How much does Entyvio cost per month?

The cash price for Entyvio is $9,135 for a 300 mg powder for intravenous (IV) injection, using an online coupon, but most people do not pay this amount. After your initial 2 injections in the first month, IV Enytvio is normally given every 8 weeks starting at week 6. It also comes as a subcutaneous (under the skin) injection that is given every 2 weeks. Continue reading

Is Entyvio an immunosuppressant or a biologic?

Entyvio (generic name: vedolizumab) is a biologic therapy approved for the treatment of ulcerative colitis and Crohn’s disease. Entyvio has no known systemic (whole body) immunosuppressive effects, but still has a risk of infections. Continue reading

How long does it take Entyvio to start working?

Entyvio may reduce your gut inflammation in about 6 weeks. Over time, Entyvio can help you to have fewer symptoms, go into remission, and reduce or stop the use of corticosteroids. In remission, your symptoms such as stomach pain and cramping, diarrhea and fatigue will go away. Continue reading

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