What are the ingredient drugs contained in Qternmet XR?
Qternmet XR contains dapagliflozin, saxagliptin and metformin hydrochloride in an extended-release tablet formulation. It was used in the treatment of adults with type-2 diabetes, but has now been discontinued.
Qternmet XR was available as extended-release tablets in the following strengths:
- dapagliflozin 2.5 mg / saxagliptin 2.5 mg / metformin hydrochlporide 1000 mg
- dapagliflozin 5 mg / saxagliptin 2.5 mg / metformin hydrochlporide 1000 mg
- dapagliflozin 5 mg / saxagliptin 5 mg / metformin hydrochlporide 1000 mg
- dapagliflozin 10 mg / saxagliptin 5 mg / metformin hydrochlporide 1000 mg
Qternmet XR was the first combination containing all three drugs. Dapagliflozin, saxagliptin and metformin hydrochloride are also contained in single ingredient products and combinations containing two of the drugs.
Dapagliflozin is a sodium‑glucose cotransporter-2 (SGLT-2) inhibitor. Dapagliflozin is also contained in the following single ingredient and combination drug products:
- dapagliflozin (Farxiga)
- dapagliflozin and saxagliptin (Qtern)
- dapagliflozin and metformin hydrochloride (Xigduo XR)
Saxagliptin is a dipeptidyl peptidase‑4 (DPP‑4) inhibitor. Saxagliptin is also contained in the following single ingredient and combination drug products:
- saxagliptin (Onglyza)
- dapagliflozin and saxagliptin (Qtern)
- saxagliptin and metformin hydrochloride (Kombiglyze XR)
Metformin hydrochloride is a biguanide. Metformin hydrochloride is also contained in the following single ingredient and combination drug products:
- metformin hydrochloride (Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet)
- dapagliflozin and metformin hydrochloride (Xigduo XR)
- saxagliptin and metformin hydrochloride (Kombiglyze XR)
Related questions
- How long does metformin take to work?
- When is the best time to take metformin?
- What is the safest diabetes medication?
Read next
Why does metformin cause diarrhea?
Metformin causes diarrhea by changing gut bacteria, affecting bile acid absorption, blocking water absorption in the intestines, and increasing gut-stimulating hormones. These combined effects make stools looser and more frequent.
Continue reading
Can you take metformin without food?
If you take metformin without food you may end up with an upset stomach, especially if you are just starting treatment. Nausea and vomiting is one of the most common side effects with metformin and can occur in over a quarter of patients. Continue reading
Does metformin lower A1C, if so how much?
When metformin is used alone as monotherapy, it lowers A1C by about 1% to 2% on average. A1C is a measure of longer-term blood sugar control. In most patients, metformin is suggested as the initial treatment for type 2 diabetes, but its glucose-lowering effect may not be adequate for all patients if used alone. Continue reading
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Drug information
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