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Can I drink alcohol while taking Entyvio?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on March 26, 2025.

Official answer

by Drugs.com

There is not a known interaction between alcohol and Entyvio (vedolizumab). However, it is important to consult your doctor before consuming alcohol while on this medication.

Potential Risks of Alcohol with Entyvio

  • Liver concerns: Entyvio can rarely cause liver problems, which may be worsened by alcohol consumption.
  • Worsening IBD symptoms: Entyvio is used to treat Crohn’s disease and ulcerative colitis, both types of inflammatory bowel disease (IBD). While research is mixed, some studies suggest alcohol may trigger or worsen IBD symptoms.

Although there is no direct interaction between Entyvio and alcohol, drinking alcohol may still have negative effects, particularly on liver health and IBD symptoms. Always check with your doctor before consuming alcohol while on Entyvio.

References
  1. Takeda Pharmaceuticals U.S.A., Inc. Entyvio: Questions & Answers. 2020. Available at: https://www.entyvio.com/frequently-asked-questions. [Accessed August 27, 2021].
  2. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Vedolizumab. Available at: https://europepmc.org/article/MED/31644050. [Accessed August 27, 2021].
  3. U.S. Department of Health & Human Services: Office on Women’s Health. Inflammatory Bowel Disease. April 1, 2019. Available at: https://www.womenshealth.gov/a-z-topics/inflammatory-bowel-disease. [Accessed August 27, 2021].
  4. Swanson GR, Sedghi S, Farhadi A, Keshavarzian A. Pattern of alcohol consumption and its effect on gastrointestinal symptoms in inflammatory bowel disease. Alcohol. 2010;44(3):223-228. doi: 10.1016/j.alcohol.2009.10.019.

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