What are the different types of buprenorphine/naloxone?
What are the different brand names? What are the different dosage forms?
Buprenorphine and naloxone is a combination medicine used for the maintenance treatment of opioid dependence in adults. It is available in sublingual film and sublingual tablet dosage forms under the brand names Suboxone, Zubsolv, Bunavail (discontinued), and Cassipa (discontinued).
Buprenorphine is a long-acting, partial opioid agonist that is used in people who are addicted to shorter-acting opioid drugs (such as heroin, hydrocodone, oxycodone, morphine and fentanyl) to reduce the withdrawal symptoms and cravings associated with opioid dependence.
Naloxone is an opioid antagonist that works to discourage people who are dependent on intravenous (IV) opioids from injecting the buprenorphine/naloxone combination.
Buprenorphine/naloxone is used as part of a complete treatment program that also includes counseling and behavioral therapy.
Because the buprenorphine/naloxone combination contains buprenorphine (which belongs to the class of drugs called narcotic analgesics) it is listed under Schedule III of the Controlled Substances Act (CSA) due to its potential for abuse.
Buprenorphine/Naloxone Formulations Available in the United States
| Brand | Dosage Form | Administration | Use | Company | Approved | Generic Available |
|---|---|---|---|---|---|---|
|
Cassipa (discontinued) |
sublingual film | once daily | opioid dependence | Teva Pharmaceuticals USA, Inc. | 2018 | No |
|
Bunavail (discontinued) |
buccal film | once daily | opioid dependence | BioDelivery Sciences International, Inc. | 2014 | No |
| Zubsolv | sublingual tablets | once daily | opioid dependence | Orexo US, Inc. | 2013 | No |
| Suboxone | sublingual film | once daily | opioid dependence | Indivior Inc. | 2010 | Yes |
|
Suboxone (discontinued) |
sublingual tablets | once daily | opioid dependence | Indivior Inc. | 2002 | Yes |
Related questions
Read next
Is buprenorphine an opiate / narcotic?
Buprenorphine is classified as an opioid partial agonist and is considered a narcotic, but It activates the mu-opioid receptor to a lesser extent than the full opioid agonists (for example: oxycodone, methadone or morphine). It's used at higher doses for opioid use disorder (opioid dependence) while generally at lower doses to treat moderate to severe pain. Continue reading
What is the difference between Sublocade and Brixadi?
Sublocade and Brixadi are both subcutaneous long-acting buprenorphine injections that may be used for the maintenance treatment of opioid misuse disorder in adults. Sublocade was approved on November 30, 2017, and Brixadi was approved on May 23, 2023. Sublocade is administered once a month, with a minimum of 26 days between doses. If extended travel is deemed necessary, a single 300mg injection may be given to cover 2 months. Brixadi is given once a week or once a month. Continue reading
How long do you take buprenorphine for?
There is no one-size-fits-all treatment duration for patients taking buprenorphine. There are many factors involved in determining the length of treatment when administering buprenorphine. Continue reading
Related medical questions
- Is Buprenex the same as buprenorphine?
- How long does Suboxone stay in your system?
- How long does Suboxone block opiates?
- Does Suboxone show up on a drug test?
- How long does Suboxone withdrawal last?
- What happens if you take opiates on Suboxone?
- How long should you wait before taking Suboxone?
- Does Suboxone help with pain?
- How long does it take for Suboxone to start working?
- Subutex vs Suboxone: What's the difference between them?
- Can you overdose on Suboxone?
- Is buprenorphine the same as Suboxone?
- Suboxone vs methadone: What’s the difference?
- Is Suboxone a controlled substance?
- How does Suboxone work?
- Is Suboxone an opiate / narcotic?
- Is acne a side effect of Suboxone?
- What medications can you NOT take with Suboxone?
- Sublocade vs Suboxone - What's the difference between them?
- Zubsolv vs Suboxone: What's the difference?
- Is Vivitrol the same as Suboxone?
- Are Bunavail and Suboxone the same thing?
- What is the difference between Cassipa and Suboxone sublingual film?
Related support groups
- Buprenorphine (40 questions, 339 members)
- Suboxone (249 questions, 5,900 members)
- Naloxone (21 questions, 67 members)
- Buprenorphine/Naloxone (11 questions, 55 members)
- Zubsolv (7 questions, 66 members)
- Bunavail (7 questions, 18 members)
- Cassipa (2 questions, 3 members)
- Opiate Dependence (150 questions, 2,362 members)
- Opiate Dependence - Maintenance (17 questions, 30 members)
- Opiate Dependence - Induction (4 questions, 8 members)