Can you buy antibiotics over the counter?
Medically reviewed by Drugs.com. Last updated on March 31, 2025.
In general, over-the-counter (OTC) oral antibiotics are not approved in the U.S.
However, there are a few OTC topical antibiotics that can be used on the skin to help prevent infections from minor scrapes, burns and wounds, such as:
- bacitracin/neomycin/polymyxin B (Neosporin and generics),
- bacitracin/polymyxin (Polysporin and generics), and
- neomycin/polymyxin/pramoxine (Neosporin Plus), which also contains pramoxine, a mild numbing medication.
Over-the-counter antibacterials, such as benzoyl peroxide, is also available for those with mild acne. Benzoyl peroxide provides a drying effect and can be bought in a generic and as brand names like Clearskin, Oxy-10, and Proactiv.
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Drug information
- Neosporin (2 reviews)
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- Polysporin (9 questions, 11 members)
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