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What is Biktarvy used for?

Medically reviewed by Melisa Puckey, BPharm. Last updated on April 3, 2024.

Official answer

by Drugs.com

Biktarvy is a tablet that contains three different antiviral medicines and is used to treat people infected with the HIV-1 virus (human immunodeficiency virus type 1).

Biktarvy can be used in patients weighing at least 14 kg who:

  • have never taken antiretroviral medicines, or
  • are replacing their current antiretroviral (ARV) medicines that they are stable on and their virus levels are suppressed (which means that the HIV-1 virus levels are less than 50 copies per mL), and they have no known or suspected substitutions associated with resistance to bictegravir or tenofovir, this means that Biktarvy can be used to treat to treat people with HIV who have suppressed viral loads with known or suspected M184V/I resistance.

When specific antiviral medicines are used in conjunction with safe sex practices to prevent HIV infection, it is called Pre-exposure prophylaxis (PrEP). Biktarvy is NOT used as PrEP.

What does HIV do to the body?

HIV is complicated in how and where it affects the body, but a simple version of what it does is:

  • HIV (human immunodeficiency virus) is a retrovirus which specifically attacks the CD4 T cells in the immune system.
  • When first infected with HIV you may not have any symptoms, but after 2 to 4 weeks people often get vague influenza, or non specific symptoms that last only a few weeks.
  • Over time if HIV is not treated the HIV virus can become high, which means the CD4 T cells levels become low. As CD4 T cells are part of the immune system, it is harder for the body to fight infections and illness.
  • You become more likely to get bacterial, fungal, viral and parasite infections and cancers that are related to viral infections. This stage of HIV infection may be called AIDS (acquired immunodeficiency syndrome)
  • Most people treated for HIV do not progress to AIDS.

Related questions

What effect does Biktarvy have on HIV?

Biktarvy contains three antiretroviral medicines (emtricitabine, tenofovir alafenamide, bictegravir) that work together to treat HIV infection by:

  • Reducing the number of HIV viruses in the blood to an undetectable level (which is less than 50 copies /mL), this means you are less likely to pass HIV to another person.
  • With less viruses in the body the CD4 T-cell count increases, so that the immune system is more able to fight infection and illness, which keeps you well.
  • HIV virus can evolve and change so that HIV medicine no longer works on it, the virus becomes drug resistant. By taking Biktarvy regularly and keeping viral numbers low, it means that there is a smaller chance of the HIV virus becoming drug resistant.

Bottom line

Biktarvy is used for HIV-1 treatment in adults and pediatric patients weighing at least 14 kg and

  • who have never taken antiretroviral, or
  • who have suppressed viral levels on a stable antiretroviral
    regimen with no known or suspected substitutions associated with resistance to
    bictegravir or tenofovir

Biktarvy is not used as PrEP to prevent HIV in at risk people.

References

Read next

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One actor and four real-life patients feature in the Biktarvy commercial “Keep loving who you are”, released on March 25th, 2020. They are Dimitri Moise, D’Eva Longoria, Zach [surname withheld], Nakeisa Jackson (Nikki), and Hugo [surname withheld]. The commercial was filmed at various locations including New York, Chicago, Atlanta, Cape May, and San Antonio. Continue reading

Does Biktarvy cause weight gain?

Weight gain is a side effect with Biktarvy, but it was reported after the drug was approved and it's not known if it was caused by the drug. Studies have shown a weight gain of between 1 and 4 kg (2.2 to 8.8 lbs) over 2 years with integrase inhibitors. Continue reading

Does Dovato cause weight gain?

Studies have shown that weight gain with Dovato can range from 2.4 to 6 kg (5.3 to 13.2 lb) or more after one year of treatment. Integrase inhibitors have been associated with significant weight gain in people living with HIV, although the exact mechanism is not fully understood. Continue reading

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