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Is Auvi-Q the same as EpiPen?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on June 12, 2024.

Official answer

by Drugs.com

Key Points

  • Auvi-Q and EpiPen are two auto-injectors that contain epinephrine. They are used to treat severe allergic reactions.
  • Auvi-Q is only available as a brand-name product, while EpiPen has generic versions available.
  • EpiPen and Auvi-Q come in different dosages and sizes.
  • Auvi-Q contains a voice instruction system that turns on when you remove the case.

For people living with certain types of allergies, epinephrine auto-injectors like Auvi-Q and EpiPen can be life-saving medications. While they both contain the same active ingredient (epinephrine) and work the same way to treat severe allergic reactions like anaphylaxis, there are a few differences between them. Below we will review 5 differences between Auvi-Q and EpiPen.

1. Auvi-Q is brand name only, EpiPen has generic versions

One difference between Auvi-Q and EpiPen is availability. Auvi-Q Is only available as a brand-name medication, and it currently does not have generic versions available. EpiPen has generic versions available. You can choose between the brand name EpiPen product or a generic one. Whether you choose a brand or generic product, these medications all work the same way to treat an allergic reaction.

2. Auvi-Q and EpiPen have different dosage forms

Another difference between Auvi-Q and EpiPen are the dosage forms they come in. Auvi-Q is available in three different dosages: 0.1 mg, 0.15 mg, and 0.3 mg. EpiPen is available in 0.15 mg (EpiPen Jr) and 0.3 mg.

Because Auvi-Q comes in a lower dose (0.1 mg), it can be used in infants and toddlers who weigh at least 16.5 lbs. EpiPen Jr can be used in children who weigh at least 33 lbs, but not less.

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3. Auvi-Q is voice-guided

Unlike EpiPen, Auvi-Q has a voice instruction system that helps guide you through the steps of using it. This can be helpful for people who do not know how to give the injection to someone who is having an allergic reaction and needs help. For those who are hearing impaired, the instructions are written on the product.

Even if the voice does not turn on, Auvi-Q will still work and you should continue to use it as directed in the instructions.

4. Auvi-Q and EpiPen are different sizes

Both Auvi-Q and EpiPen are auto-injectors and can be injected into the muscle or under the skin of the thigh during an allergic reaction. However, they come in different sizes.

EpiPen and generics are pen shaped, and are around 6 inches long and 1 inch wide. Auvi-Q is a box shape, and is about 3.5 inches long and 2 inches wide. The manufacturer claims it can fit in your pocket.

5. EpiPen has a slightly longer injection time

Auto-injectors are easy to use, since you only need to press them firmly against the thigh. They can even be injected through clothing if needed. The time it takes for each EpiPen and Auvi-Q to finish the injection is different.

With EpiPen, you need to firmly hold it in place for 3 seconds. Auvi-Q, however, has a hold time of 2 seconds. Both auto-injectors must be held in place for the recommended times for them to work properly.

This is not all of the information you need to know about using EpiPen or Auvi-Q safely. Make sure to review the Instructions of Use that came with your product, and ask your prescriber if you have any questions.

References

Auvi-Q [package insert]. (Revised Mar 2024). kaleo, Inc. Accessed 06/12/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6180fb40-7fca-4602-b3da-ce62b8cd2470

EpiPen, EpiPen Jr [package insert]. (Revised Feb 2023). Mylan Specialty L.P. Accessed 06/12/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7560c201-9246-487c-a13b-6295db04274a

Guerlain, S., et. al. (2010). A comparison of 4 epinephrine autoinjector delivery systems: usability and patient preference. In: Annals of Allergy, Asthma & Immunology. Accessed 06/12/2024 at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892620/

Kessler, C., et. al. (2019). Usability and preference of epinephrine auto-injectors: Auvi-Q and EpiPen Jr. In: Annals of Allergy, Asthma & Immunology. Accessed 06/12/2024 at https://www.sciencedirect.com/science/article/pii/S1081120619304375

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