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Does aspirin lower blood pressure?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on Dec 10, 2024.

Official answer

by Drugs.com

No, aspirin does not appear to affect blood pressure. The effects of aspirin on blood pressure have been studied at doses even higher than 1,500 mg per day, as well as low doses for an average of 4 years. These studies showed that aspirin does not have an effect on blood pressure.

A 2024 systematic review and meta-analysis looked at whether aspirin affects blood pressure in people with hypertension (high blood pressure). It included five studies made up of about 20,000 patients. Researchers found that aspirin did not affect systolic blood pressure or diastolic blood pressure in these patients.

According to the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, non-steroidal inflammatory drugs (NSAIDs) are listed as a class of medications associated with high blood pressure. While other NSAIDs have been linked to elevations in blood pressure, recent studies have shown that aspirin does not share this effect.

If you notice changes in your blood pressure, consult your healthcare provider. They can help you determine the cause and offer guidance on how to maintain your blood pressure within a healthy range.

References

Chobanian, A.V., et al. 2004. National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. In: JAMA. Accessed on 12/10/2024 at https://www.nhlbi.nih.gov/files/docs/guidelines/jnc7full.pdf

Li, Z., et. al. 2024. Effect of aspirin on blood pressure in hypertensive patients: a systematic review and meta-analysis. In: BMC Cardiovascular Disorders. DOI: https://doi.org/10.1186/s12872-024-03737-x

Sherve, K., et. al. 2014. Cardiovascular Effects of NSAIDs. In: American Family Physician. Accessed 12/09/2024 at https://www.aafp.org/pubs/afp/issues/2014/0815/od2.html

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