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Platelet aggregation inhibitors

What are Platelet aggregation inhibitors?

Platelet aggregation inhibitors work in different places of the clotting cascade and prevent platelet adhesion, therefore no clot formation.

Aspirin, the most commonly used antiplatelet drug changes the balance between prostacyclin (which inhibits platelet aggregation) and thromboxane (that promotes aggregation). It irreversibly inhibits the enzyme cyclo-oxygenase, which leads to reduction in thromboxane synthesis in platelets and prostacyclin in vascular endothelial cells. The vascular endothelium recovers and can synthesize more prostacyclin but thromboxane synthesis only recovers after new platelets are formed.

Platelet aggregation inhibitors are used acutely in myocardial infarction, atrial fibrillation, following coronary bypass, angioplasty and stenting. It is also used as prophylaxis to prevent myocardial infarction and stroke.

List of Platelet aggregation inhibitors

View by  Generic | Brand
Drug Name Avg. Rating Reviews
ticagrelor systemic (Pro)
Brand name: Brilinta
3.8
115 reviews
clopidogrel systemic (Pro)
Brand name: Plavix
7.1
101 reviews
aspirin systemic (Pro)
Brand names: Arthritis Pain, Ascriptin, Aspergum, Aspi-Cor, Aspir-Low, Aspiritab, Aspirtab, Bayer Aspirin, Bayer Aspirin Extra Strength Plus, Bayer Aspirin Regimen, Bayer Children's Aspirin, Durlaza, Easprin, Ecotrin, Ecpirin, Entercote, Genacote, Halfprin, Miniprin, Norwich Aspirin, Vazalore
7.9
49 reviews
prasugrel systemic (Pro)
Brand name: Effient
6.3
29 reviews
aspirin / dipyridamole systemic (Pro)
Brand name: Aggrenox
7.1
18 reviews
cilostazol systemic (Pro)
6.5
15 reviews
dipyridamole systemic (Pro)
Brand name: Persantine
1.0
1 review
ticlopidine systemic
No reviews
caplacizumab systemic (Pro)
Brand name: Cablivi
No reviews
cangrelor systemic (Pro)
Brand name: Kengreal
No reviews
aspirin / omeprazole systemic (Pro)
Brand name: Yosprala
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.