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Zaltrap and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Zaltrap (ziv-aflibercept).

Moderate

Ziv-Aflibercept High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

ziv-aflibercept - hypertension

The use of ziv-aflibercept increases the risk of Grade 3-4 hypertension. It is recommended to monitor blood pressure every two weeks or more frequently as clinically indicated during treatment. Patients should be treated with appropriate antihypertensive therapy and continue monitoring blood pressure regularly. Care should be exercised when treating patients with preexisting hypertension. Temporarily suspend treatment in patients with uncontrolled hypertension until controlled and permanently reduce the dose to 2 mg per kg for subsequent cycles. Discontinue therapy with ziv-aflibercept in patients with hypertensive crisis or hypertensive encephalopathy.

References

  1. (2012) "Product Information. Zaltrap (ziv-aflibercept)." sanofi-aventis

Zaltrap drug interactions

There are 163 drug interactions with Zaltrap (ziv-aflibercept).

Zaltrap disease interactions

There are 6 disease interactions with Zaltrap (ziv-aflibercept) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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