Zepzelca and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Zepzelca (lurbinectedin).
Lurbinectedin Food
Major Food Interaction
Do not consume Seville oranges, grapefruit, grapefruit juice, or any supplements that contain grapefruit extract during treatment with lurbinectedin unless directed otherwise by your doctor. Grapefruit and Seville oranges may increase the blood levels of lurbinectedin. This may increase side effects such as liver problems and impaired bone marrow function resulting in low numbers of different types of blood cells. You may also be more likely to develop anemia, bleeding problems, or infections due to low blood cell counts. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Zepzelca drug interactions
There are 426 drug interactions with Zepzelca (lurbinectedin).
Zepzelca disease interactions
There are 2 disease interactions with Zepzelca (lurbinectedin) which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
