Fluorouracil and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with fluorouracil.
Fluorouracil Multivitamins With Minerals
Major Drug Interaction
Products containing folic acid may increase the effects of fluorouracil. You may be more likely to develop serious side effects such as anemia, bleeding problems, infections, and nerve damage when these medications are used together. Contact your doctor if you experience severe nausea and vomiting, diarrhea, paleness of skin, fatigue, dizziness, fainting, unusual bleeding or bruising, blood in the stools, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Fluorouracil drug interactions
There are 289 drug interactions with fluorouracil.
Fluorouracil disease interactions
There are 6 disease interactions with fluorouracil which include:
- myelosuppression
- infections
- stomatitis
- bleeding
- coronary artery disease
- dihydropyrimidine dehydrogenase (DPD) deficiency
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- During pregnancy
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- Drug class: antimetabolites
- Breastfeeding
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.