Duexis and Alcohol/Food Interactions
There are 5 alcohol/food/lifestyle interactions with Duexis (famotidine / ibuprofen).
Ibuprofen Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using ibuprofen together with ethanol (alcohol). Do not drink alcohol while taking ibuprofen. Alcohol can increase your risk of stomach bleeding caused by ibuprofen. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Ibuprofen Alcohol (Ethanol)
Minor Drug Interaction
Information for this minor interaction is available on the professional version.
Ibuprofen Nicotine
Minor Drug Interaction
Information for this minor interaction is available on the professional version.
Famotidine Nicotine
Minor Drug Interaction
Information for this minor interaction is available on the professional version.
Ibuprofen High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
NSAIDs - fluid retention
Fluid retention and edema have been reported in association with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), including some topical formulations. NSAIDs (including topicals) can lead to new onset of hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. NSAIDs should be used with caution in patients with preexisting fluid retention, hypertension, or history of heart failure. NSAIDs should be avoided in patients with severe heart failure unless the benefits are expected to outweigh the risk of worsening heart failure; if an NSAID is used in such patients, they should be monitored for signs of worsening heart failure. Blood pressure and cardiovascular status should be monitored closely during the initiation of NSAID treatment and throughout the course of therapy.
Duexis drug interactions
There are 615 drug interactions with Duexis (famotidine / ibuprofen).
Duexis disease interactions
There are 13 disease interactions with Duexis (famotidine / ibuprofen) which include:
- GI bleeding
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- renal dysfunction
- PKU
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
More about Duexis (famotidine / ibuprofen)
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- FDA approval history
- Drug class: Nonsteroidal anti-inflammatory drugs
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.