Skip to main content

Dobutrex and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with Dobutrex (dobutamine).

Moderate

Dobutamine Caffeine

Moderate Drug Interaction

Both DOBUTamine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Major

Dobutamine High Blood Pressure (Hypertension)

Major Potential Hazard, Moderate plausibility

dobutamine/arbutamine - arrhythmias

Dobutamine and arbutamine produce stimulation of the beta receptors of the heart. The use of these agents has been associated with an increase in heart rate, ventricular ectopy, atrial fibrillation, hypertension, enhanced A-V conduction, and arrhythmias. Therapy with dobutamine or arbutamine should be administered cautiously in patients with cardiac conduction disorders.

References

  1. Bianchi C, Diaz R, Gonzales C, Beregovich J (1975) "Effects of dobutamine on atrioventricular conduction." Am Heart J, 90, p. 474-8
  2. (2002) "Product Information. Dobutrex (dobutamine)." Lilly, Eli and Company
  3. Baudhuin T, Marwick T, Melin J, Wijns W, D'Hondt AM, Detry JM (1993) "Diagnosis of coronary artery disease in elderly patients: safety and efficacy of dobutamine echocardiography." Eur Heart J, 14, p. 799-803
  4. Poldermans D, Fioretti PM, Boersma E, Forster T, Vanurk H, Cornel JH, Arnese M, Roelandt JRTC (1994) "Safety of dobutamine-atropine stress echocardiography in patients with suspected or proven coronary artery disease." Am J Cardiol, 73, p. 456-9
  5. Picano E, Mathias W, Pingitore A, Bigi R, Previtali M (1994) "Safety and tolerability of dobutamine-atropine stress echocardiography: a prospective, multicentre study." Lancet, 344, p. 1190-2
  6. Kinder C, Chamberlain J, Kall J, Kopp D, Johnson M, Costanzo MR, Wilber D (1994) "Prognostic significance of sustained ventricular tachyarrhythmia occurring during dobutamine infusion." J Heart Lung Transplant, 13, p. 1045-50
  7. Cohen A, Chauvel C, Benhalima B, Blanchard B (1995) "Complication of dobutamine stress echocardiography." Lancet, 345, p. 201-2
  8. Tisdale JE, Patel R, Webb CR, Borzak S, Zarowitz BJ (1995) "Electrophysiologic and proarrhythmic effects of intravenous inotropic agents." Prog Cardiovasc Dis, 38, p. 167-80
  9. Previtali M, Lanzarini L, Fetiveau R, Poli A, Diotallevi P (1996) "Dobutamine-induced and spontaneous sustained ventricular tachycardia in recent myocardial infarction." Eur Heart J, 17, p. 803-4
  10. (2001) "Product Information. GenESA (arbutamine)." Gensia Inc
View all 10 references

Dobutrex drug interactions

There are 174 drug interactions with Dobutrex (dobutamine).

Dobutrex disease interactions

There are 5 disease interactions with Dobutrex (dobutamine) which include:

Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer