Alka-Seltzer Original and Alcohol/Food Interactions
There are 4 alcohol/food/lifestyle interactions with Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate).
Aspirin Caffeine
Moderate Drug Interaction
Using sodium bicarbonate together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Aspirin Caffeine
Minor Drug Interaction
Information for this minor interaction is available on the professional version.
Aspirin Alcohol (Ethanol)
Moderate Drug Interaction
Using sodium bicarbonate together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Aspirin Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using aspirin together with ethanol (alcohol). Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Alka-Seltzer Original drug interactions
There are 468 drug interactions with Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate).
Alka-Seltzer Original disease interactions
There are 11 disease interactions with Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) which include:
- sodium/water balance
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- acid/base balance
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
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More about Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate)
- Alka-Seltzer Original consumer information
- Check interactions
- Compare alternatives
- Reviews (4)
- Side effects
- Drug class: salicylates
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.